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- W3146563344 abstract "The extraction of soluble polysaccharides from the whole herb of Talinum triangulare was optimized using onefactor-at-a-time and L9(34) orthogonal array design methods. The extraction efficiency of polysaccharides was investigated as a function of temperature, time and solid-to-solvent ratio. The antitumor activity of the extracted polysaccharides was evaluated by examining their effects on the proliferation of human cancer HepG2 cells using MTT assay and trypan blue staining. Results indicated that the optimal conditions for extracting soluble polysaccharides from T. triangulare were found as follows: extraction temperature of 100 ℃, extraction time of 2.0 h, solid-to-solvent ratio of 1:25(g/mL) and 2 extraction cycles(repeated twice). The yield of polysaccharides under the optimized conditions was 14.99%. The extracted polysaccharides exhibited a potent antitumor activity in vitro as indicated by their significant inhibition on the proliferation of HepG2 cells and reduction of their survival in a concentration- and time-dependent manner." @default.
- W3146563344 created "2021-04-13" @default.
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- W3146563344 date "2013-01-01" @default.
- W3146563344 modified "2023-09-27" @default.
- W3146563344 title "Extraction and Antitumor Activity of Polysaccharides from Talinum triangulare" @default.
- W3146563344 hasPublicationYear "2013" @default.
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