Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146880384> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W3146880384 endingPage "63" @default.
- W3146880384 startingPage "54" @default.
- W3146880384 abstract "临床的试用为多巴胺神经原表明了能力，宫外地移植了进 striatum 到 structurallyintegrate ，恢复多巴胺传播，并且导致长期的功能的好处因为 Parkinson 是疾病( PD ) patients.Despite 原则的这个证明，很多限制在 thepast 上妨碍了房间代替治疗的开发 20 年，特别地主机大脑的织物可获得性，接枝幸存，和足够的神经分布。与在优先的临床的试用的失败的 greaterunderstanding，增加了中脑多巴胺的知识开发(包括 Wnts 的现在) ，和 pluripotent 干细胞技术的发展，我们更好比平常被装备使重新致力很多 thesechallenges。这评论为 PD 在房间代替治疗总结试用，磨难，和进步。我们讨论正规的 modulating 和发信号改进在 dopamineneural 开发和成年大脑在他们的角色之上基于的房间治疗的不在经典中的 Wnt 的 theprospects。这将包括 Wnts 的潜力到(i) 在 vitro 和后面的移植扩展胎儿地导出的织物，(ii ) 支持 pluripotent 干细胞的区别，(iii ) 增加神经电路的接枝 integrationand 恢复，并且(iv ) 最后提高接枝幸存。" @default.
- W3146880384 created "2021-04-13" @default.
- W3146880384 creator A5059011839 @default.
- W3146880384 creator A5063925481 @default.
- W3146880384 creator A5065801518 @default.
- W3146880384 creator A5075950525 @default.
- W3146880384 date "2014-01-01" @default.
- W3146880384 modified "2023-09-24" @default.
- W3146880384 title "Modulating Wnt signaling to improve cell replacement therapy for Parkinson＇s disease" @default.
- W3146880384 hasPublicationYear "2014" @default.
- W3146880384 type Work @default.
- W3146880384 sameAs 3146880384 @default.
- W3146880384 citedByCount "0" @default.
- W3146880384 crossrefType "journal-article" @default.
- W3146880384 hasAuthorship W3146880384A5059011839 @default.
- W3146880384 hasAuthorship W3146880384A5063925481 @default.
- W3146880384 hasAuthorship W3146880384A5065801518 @default.
- W3146880384 hasAuthorship W3146880384A5075950525 @default.
- W3146880384 hasConcept C104317684 @default.
- W3146880384 hasConcept C107459253 @default.
- W3146880384 hasConcept C126322002 @default.
- W3146880384 hasConcept C137620995 @default.
- W3146880384 hasConcept C145103041 @default.
- W3146880384 hasConcept C169760540 @default.
- W3146880384 hasConcept C185592680 @default.
- W3146880384 hasConcept C2779134260 @default.
- W3146880384 hasConcept C2779734285 @default.
- W3146880384 hasConcept C2780062018 @default.
- W3146880384 hasConcept C513476851 @default.
- W3146880384 hasConcept C55493867 @default.
- W3146880384 hasConcept C62478195 @default.
- W3146880384 hasConcept C71924100 @default.
- W3146880384 hasConcept C86803240 @default.
- W3146880384 hasConcept C95444343 @default.
- W3146880384 hasConcept C98274493 @default.
- W3146880384 hasConceptScore W3146880384C104317684 @default.
- W3146880384 hasConceptScore W3146880384C107459253 @default.
- W3146880384 hasConceptScore W3146880384C126322002 @default.
- W3146880384 hasConceptScore W3146880384C137620995 @default.
- W3146880384 hasConceptScore W3146880384C145103041 @default.
- W3146880384 hasConceptScore W3146880384C169760540 @default.
- W3146880384 hasConceptScore W3146880384C185592680 @default.
- W3146880384 hasConceptScore W3146880384C2779134260 @default.
- W3146880384 hasConceptScore W3146880384C2779734285 @default.
- W3146880384 hasConceptScore W3146880384C2780062018 @default.
- W3146880384 hasConceptScore W3146880384C513476851 @default.
- W3146880384 hasConceptScore W3146880384C55493867 @default.
- W3146880384 hasConceptScore W3146880384C62478195 @default.
- W3146880384 hasConceptScore W3146880384C71924100 @default.
- W3146880384 hasConceptScore W3146880384C86803240 @default.
- W3146880384 hasConceptScore W3146880384C95444343 @default.
- W3146880384 hasConceptScore W3146880384C98274493 @default.
- W3146880384 hasIssue "1" @default.
- W3146880384 hasLocation W31468803841 @default.
- W3146880384 hasOpenAccess W3146880384 @default.
- W3146880384 hasPrimaryLocation W31468803841 @default.
- W3146880384 hasRelatedWork W2027317254 @default.
- W3146880384 hasRelatedWork W2100519706 @default.
- W3146880384 hasRelatedWork W2113810705 @default.
- W3146880384 hasRelatedWork W2116923888 @default.
- W3146880384 hasRelatedWork W2333107205 @default.
- W3146880384 hasRelatedWork W2462589623 @default.
- W3146880384 hasRelatedWork W2464921777 @default.
- W3146880384 hasRelatedWork W2494489764 @default.
- W3146880384 hasRelatedWork W2613162658 @default.
- W3146880384 hasRelatedWork W2898660101 @default.
- W3146880384 hasRelatedWork W2964682226 @default.
- W3146880384 hasRelatedWork W2989672020 @default.
- W3146880384 hasRelatedWork W3123073118 @default.
- W3146880384 hasRelatedWork W3142172770 @default.
- W3146880384 hasRelatedWork W3151984967 @default.
- W3146880384 hasRelatedWork W3157557348 @default.
- W3146880384 hasRelatedWork W3164820646 @default.
- W3146880384 hasRelatedWork W3186180571 @default.
- W3146880384 hasRelatedWork W3212665259 @default.
- W3146880384 hasRelatedWork W2775349779 @default.
- W3146880384 isParatext "false" @default.
- W3146880384 isRetracted "false" @default.
- W3146880384 magId "3146880384" @default.
- W3146880384 workType "article" @default.