Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146931405> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3146931405 abstract "The mechanism(s) of inhibition of endothelium-dependent relaxation (EDR) by oxidized low-density lipoprotein (Ox-LDL) was examined in isolated porcine coronary arteries and rabbit aortas. Incubation with Ox-LDL but not native LDL caused the inhibition of thrombin- or acetylcholine-induced EDR, whereas A23187-induced EDR was preserved after incubation with Ox-LDL. Lysophosphatidylcholine (lysoPC), which was abundant in Ox-LDL and was found to be transferred from Ox-LDL to endothelial cells, also caused the inhibition of EDR in response to thrombin or acetylcholine but not to A23187. Ox-LDL depleted of lysoPC, which was prepared by phospholipase B, failed to inhibit the vasorelaxation. Coincubation with staurosporine or calphostin C, potent inhibitors of protein kinase C, attenuated the EDR inhibition by Ox-LDL or lysoPC. Phorbol 12-myristate 13-acetate, a specific protein kinase C activator, caused the EDR inhibition, and its effect was attenuated by staurosporine or calphostin C. Furthermore, lysoPC was c..." @default.
- W3146931405 created "2021-04-13" @default.
- W3146931405 creator A5017436436 @default.
- W3146931405 creator A5028695604 @default.
- W3146931405 creator A5033026872 @default.
- W3146931405 creator A5045745965 @default.
- W3146931405 creator A5058077187 @default.
- W3146931405 creator A5072312665 @default.
- W3146931405 creator A5087031229 @default.
- W3146931405 date "1993-01-01" @default.
- W3146931405 modified "2023-09-23" @default.
- W3146931405 title "Protein kinase C inhibitors prevent impairment of endothelium-dependent relaxation by oxidatively modified LDL." @default.
- W3146931405 hasPublicationYear "1993" @default.
- W3146931405 type Work @default.
- W3146931405 sameAs 3146931405 @default.
- W3146931405 citedByCount "0" @default.
- W3146931405 crossrefType "journal-article" @default.
- W3146931405 hasAuthorship W3146931405A5017436436 @default.
- W3146931405 hasAuthorship W3146931405A5028695604 @default.
- W3146931405 hasAuthorship W3146931405A5033026872 @default.
- W3146931405 hasAuthorship W3146931405A5045745965 @default.
- W3146931405 hasAuthorship W3146931405A5058077187 @default.
- W3146931405 hasAuthorship W3146931405A5072312665 @default.
- W3146931405 hasAuthorship W3146931405A5087031229 @default.
- W3146931405 hasConcept C126322002 @default.
- W3146931405 hasConcept C134018914 @default.
- W3146931405 hasConcept C170493617 @default.
- W3146931405 hasConcept C184235292 @default.
- W3146931405 hasConcept C185592680 @default.
- W3146931405 hasConcept C195794163 @default.
- W3146931405 hasConcept C2776330855 @default.
- W3146931405 hasConcept C2777292125 @default.
- W3146931405 hasConcept C2778596009 @default.
- W3146931405 hasConcept C2778918659 @default.
- W3146931405 hasConcept C2779084600 @default.
- W3146931405 hasConcept C2780043322 @default.
- W3146931405 hasConcept C2780245509 @default.
- W3146931405 hasConcept C2781168148 @default.
- W3146931405 hasConcept C41625074 @default.
- W3146931405 hasConcept C55493867 @default.
- W3146931405 hasConcept C71924100 @default.
- W3146931405 hasConcept C86803240 @default.
- W3146931405 hasConcept C88045685 @default.
- W3146931405 hasConcept C89560881 @default.
- W3146931405 hasConcept C97029542 @default.
- W3146931405 hasConceptScore W3146931405C126322002 @default.
- W3146931405 hasConceptScore W3146931405C134018914 @default.
- W3146931405 hasConceptScore W3146931405C170493617 @default.
- W3146931405 hasConceptScore W3146931405C184235292 @default.
- W3146931405 hasConceptScore W3146931405C185592680 @default.
- W3146931405 hasConceptScore W3146931405C195794163 @default.
- W3146931405 hasConceptScore W3146931405C2776330855 @default.
- W3146931405 hasConceptScore W3146931405C2777292125 @default.
- W3146931405 hasConceptScore W3146931405C2778596009 @default.
- W3146931405 hasConceptScore W3146931405C2778918659 @default.
- W3146931405 hasConceptScore W3146931405C2779084600 @default.
- W3146931405 hasConceptScore W3146931405C2780043322 @default.
- W3146931405 hasConceptScore W3146931405C2780245509 @default.
- W3146931405 hasConceptScore W3146931405C2781168148 @default.
- W3146931405 hasConceptScore W3146931405C41625074 @default.
- W3146931405 hasConceptScore W3146931405C55493867 @default.
- W3146931405 hasConceptScore W3146931405C71924100 @default.
- W3146931405 hasConceptScore W3146931405C86803240 @default.
- W3146931405 hasConceptScore W3146931405C88045685 @default.
- W3146931405 hasConceptScore W3146931405C89560881 @default.
- W3146931405 hasConceptScore W3146931405C97029542 @default.
- W3146931405 hasLocation W31469314051 @default.
- W3146931405 hasOpenAccess W3146931405 @default.
- W3146931405 hasPrimaryLocation W31469314051 @default.
- W3146931405 hasRelatedWork W1681081906 @default.
- W3146931405 hasRelatedWork W1967117412 @default.
- W3146931405 hasRelatedWork W1970539529 @default.
- W3146931405 hasRelatedWork W1988273670 @default.
- W3146931405 hasRelatedWork W1992513577 @default.
- W3146931405 hasRelatedWork W1994946013 @default.
- W3146931405 hasRelatedWork W2021533601 @default.
- W3146931405 hasRelatedWork W2026658981 @default.
- W3146931405 hasRelatedWork W2046160723 @default.
- W3146931405 hasRelatedWork W2078414710 @default.
- W3146931405 hasRelatedWork W2085285080 @default.
- W3146931405 hasRelatedWork W2125611568 @default.
- W3146931405 hasRelatedWork W2134494574 @default.
- W3146931405 hasRelatedWork W2151035518 @default.
- W3146931405 hasRelatedWork W2155718230 @default.
- W3146931405 hasRelatedWork W2170436017 @default.
- W3146931405 hasRelatedWork W2409678232 @default.
- W3146931405 hasRelatedWork W2464616972 @default.
- W3146931405 hasRelatedWork W3145768564 @default.
- W3146931405 hasRelatedWork W3147137825 @default.
- W3146931405 isParatext "false" @default.
- W3146931405 isRetracted "false" @default.
- W3146931405 magId "3146931405" @default.
- W3146931405 workType "article" @default.