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• W3146987016 abstract "To further enhance the biological properties of acid-etched microrough titanium surfaces, titania nanotex- tured thin films were produced by simple chemical oxidation, without significantly altering the existing topographical and roughness features. The nanotextured layers on titanium surfaces can be controllably varied by tuning the oxidation duration time. The oxidation treatment significantly reduced water contact angles and increased the surface energy com- pared to the surfaces prior to oxidation. The murine bone marrow stromal cells (BMSCs) were used to evaluate the bioactivity. In comparison, oxidative nanopatterning of mi- crorough titanium surfaces led to improved attachment and proliferation of BMSCs. The rate of osteoblastic differenti- ation was also represented by the increased levels of alkaline phosphatase activity and mineral deposition. These data indicated that oxidative nanopatterning enhanced the bio- logical properties of the microrough titanium surfaces by modulating their surface chemistry and nanotopography. Based on the proven mechanical interlocking ability of microtopographies, enhancement of multiple osteoblast functions attained by this oxidative nanopatterning is expected to lead to better implant osseointegration in vivo." @default.
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• W3146987016 date "2014-01-01" @default.
• W3146987016 modified "2023-09-27" @default.
• W3146987016 title "Controlled oxidative nanopatterning of microrough titanium surfaces for improving osteogenic activity" @default.
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• W3146987016 hasPublicationYear "2014" @default.
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