Matches in SemOpenAlex for { <https://semopenalex.org/work/W3147030700> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3147030700 abstract "The Hantzsch esters derivatives have been attracted much attention for their pharmacological properties. The primary pharmaceutical application of these compounds are the treatment of cardiovascular diseases, such as hypertension. It has also found to show many promising bioactivities such as antibacterial, antioxidant, and anticancer. Besides, the Hantzsch esters also powerful reducing agents in the hydrogenation transfer reaction. Therefore, several methods to afford Hantzsch esters have been developed, such as the classical method, the use of microwaves, including the utilization of various catalysts. However, these methods have disadvantages such as long reaction time, low yields, relatively expensive reagents, and challenge in separation. In continuation of effort towards the development of efficient synthetic procedures, Hantzsch ester synthesis research carried out of the one-pot three-components reaction of aldehydes, ethyl acetoacetate, and ammonium acetate in ethanol solvents using the reflux method which is monitored by TLC. The pure products have obtained by recrystallization. The product structure has been confirmed by melting point and spectroscopc data including UV, IR, 1H-NMR, 13C-NMR, HSQC, and HMBC. In conclusion, a simple and highly efficient method for one-pot three-component synthesis of Hantzsch esters from various aromatic and aliphatic aldehydes, ethyl acetoacetate, and ammonium acetate get a good yield. The simple experimental protocol, mild conditions, avoiding the use of any catalyst, and good yields are the advantages of this procedure. This research is part of the synthesis of dihydrochalcone through the hydrogenation transfer reaction." @default.
- W3147030700 created "2021-04-13" @default.
- W3147030700 creator A5012300397 @default.
- W3147030700 creator A5034068525 @default.
- W3147030700 creator A5060214928 @default.
- W3147030700 creator A5071265312 @default.
- W3147030700 creator A5086221539 @default.
- W3147030700 date "2021-01-01" @default.
- W3147030700 modified "2023-10-18" @default.
- W3147030700 title "A simple synthesis of Hantzsch esters derivatives as proton donors in the hydrogenation transfer reaction" @default.
- W3147030700 cites W1968568177 @default.
- W3147030700 cites W1991992168 @default.
- W3147030700 cites W1993367766 @default.
- W3147030700 cites W1997077390 @default.
- W3147030700 cites W2011132528 @default.
- W3147030700 cites W2012742483 @default.
- W3147030700 cites W2019041907 @default.
- W3147030700 cites W2021602221 @default.
- W3147030700 cites W2025828989 @default.
- W3147030700 cites W2050253833 @default.
- W3147030700 cites W2082916506 @default.
- W3147030700 cites W2083638273 @default.
- W3147030700 cites W2084009401 @default.
- W3147030700 cites W2091867567 @default.
- W3147030700 cites W2115041061 @default.
- W3147030700 cites W2122334502 @default.
- W3147030700 cites W2127378043 @default.
- W3147030700 cites W2143176194 @default.
- W3147030700 cites W2174072579 @default.
- W3147030700 cites W2950430336 @default.
- W3147030700 cites W2950960588 @default.
- W3147030700 cites W2952940877 @default.
- W3147030700 doi "https://doi.org/10.1063/5.0042003" @default.
- W3147030700 hasPublicationYear "2021" @default.
- W3147030700 type Work @default.
- W3147030700 sameAs 3147030700 @default.
- W3147030700 citedByCount "0" @default.
- W3147030700 crossrefType "proceedings-article" @default.
- W3147030700 hasAuthorship W3147030700A5012300397 @default.
- W3147030700 hasAuthorship W3147030700A5034068525 @default.
- W3147030700 hasAuthorship W3147030700A5060214928 @default.
- W3147030700 hasAuthorship W3147030700A5071265312 @default.
- W3147030700 hasAuthorship W3147030700A5086221539 @default.
- W3147030700 hasBestOaLocation W31470307001 @default.
- W3147030700 hasConcept C114373084 @default.
- W3147030700 hasConcept C134121241 @default.
- W3147030700 hasConcept C161790260 @default.
- W3147030700 hasConcept C178790620 @default.
- W3147030700 hasConcept C179998833 @default.
- W3147030700 hasConcept C185592680 @default.
- W3147030700 hasConcept C191897082 @default.
- W3147030700 hasConcept C192562407 @default.
- W3147030700 hasConcept C202751555 @default.
- W3147030700 hasConcept C21951064 @default.
- W3147030700 hasConcept C2776308844 @default.
- W3147030700 hasConcept C2776715866 @default.
- W3147030700 hasConcept C2779858419 @default.
- W3147030700 hasConcept C2780782300 @default.
- W3147030700 hasConcept C40875361 @default.
- W3147030700 hasConcept C535685238 @default.
- W3147030700 hasConcept C55493867 @default.
- W3147030700 hasConcept C555196967 @default.
- W3147030700 hasConceptScore W3147030700C114373084 @default.
- W3147030700 hasConceptScore W3147030700C134121241 @default.
- W3147030700 hasConceptScore W3147030700C161790260 @default.
- W3147030700 hasConceptScore W3147030700C178790620 @default.
- W3147030700 hasConceptScore W3147030700C179998833 @default.
- W3147030700 hasConceptScore W3147030700C185592680 @default.
- W3147030700 hasConceptScore W3147030700C191897082 @default.
- W3147030700 hasConceptScore W3147030700C192562407 @default.
- W3147030700 hasConceptScore W3147030700C202751555 @default.
- W3147030700 hasConceptScore W3147030700C21951064 @default.
- W3147030700 hasConceptScore W3147030700C2776308844 @default.
- W3147030700 hasConceptScore W3147030700C2776715866 @default.
- W3147030700 hasConceptScore W3147030700C2779858419 @default.
- W3147030700 hasConceptScore W3147030700C2780782300 @default.
- W3147030700 hasConceptScore W3147030700C40875361 @default.
- W3147030700 hasConceptScore W3147030700C535685238 @default.
- W3147030700 hasConceptScore W3147030700C55493867 @default.
- W3147030700 hasConceptScore W3147030700C555196967 @default.
- W3147030700 hasLocation W31470307001 @default.
- W3147030700 hasOpenAccess W3147030700 @default.
- W3147030700 hasPrimaryLocation W31470307001 @default.
- W3147030700 hasRelatedWork W11740360 @default.
- W3147030700 hasRelatedWork W12723628 @default.
- W3147030700 hasRelatedWork W18213395 @default.
- W3147030700 hasRelatedWork W2252714 @default.
- W3147030700 hasRelatedWork W28332489 @default.
- W3147030700 hasRelatedWork W31345669 @default.
- W3147030700 hasRelatedWork W31775510 @default.
- W3147030700 hasRelatedWork W5694422 @default.
- W3147030700 hasRelatedWork W7688257 @default.
- W3147030700 hasRelatedWork W9059960 @default.
- W3147030700 isParatext "false" @default.
- W3147030700 isRetracted "false" @default.
- W3147030700 magId "3147030700" @default.
- W3147030700 workType "article" @default.