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• W3147098950 abstract "We read with interest the article by He and associates on comparing the clinical outcomes of wavefront-guided and wavefront-optimized in situ keratomileusis (LASIK). 1 He L. Liu A. Manche E.E. Wavefront-guided versus wavefront-optimized laser in situ keratomileusis for patients with myopia: a prospective randomized contralateral eye study. Am J Ophthalmol. 2014; 157: 1170-1178 Abstract Full Text Full Text PDF PubMed Scopus (34) Google Scholar They found both treatments were able to correct myopia safely and effectively; however, the wavefront-guided treatment platforms appeared to offer significant advantages in terms of residual refractive error, uncorrected distance acuity, and contrast sensitivity. The study was undoubtedly well designed and was a controlled clinical study, which could meet the expected high standard of phase III clinical trials regulated by the US Food and Drug Administration (FDA). However, our concern is that some medical researchers pay little attention or neglect to deal with the concept of multiplicity of hypothesis, which is rigorously applied between statisticians. Wavefront-Guided Versus Wavefront-Optimized Laser in situ Keratomileusis for Patients With Myopia: A Prospective Randomized Contralateral Eye StudyAmerican Journal of OphthalmologyVol. 157Issue 6PreviewTo compare the clinical outcomes of wavefront-guided and wavefront-optimized laser in situ keratomileusis (LASIK). Full-Text PDF ReplyAmerican Journal of OphthalmologyVol. 158Issue 6PreviewWe appreciate Drs Na, Hwang, and Park's comments regarding the biostatistical analysis of the data in our manuscript. We agree with their comments regarding the treatment of multiple outcome measures and the importance of applying the Bonferroni correction to solve multiple testing problems attributable to the dependency among a number of hypotheses. We would like to clarify a number of points they raised. Full-Text PDF" @default.
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• W3147098950 date "2014-12-01" @default.
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• W3147098950 title "Wavefront-Guided Versus Wavefront-Optimized Laser In Situ Keratomileusis for Patients With Myopia: A Prospective Randomized Contralateral Eye Study" @default.
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• W3147098950 doi "https://doi.org/10.1016/j.ajo.2014.09.004" @default.
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