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• W3147175512 abstract "The effect of age on the motor protein myosin was examined in a novel in vitro motility assay. Myosin was extracted from soleus fibres of young (3-6 month) and old (20-24 month) rats. All fibres expressed the type I myosin heavy chain (MyHC) and the slow isoforms of the myosin light chains (MyLCs). In vitro motility speed was significantly (P < 0.001) faster in the young adult (1.43 +/- 0.23 microm s-1) than in the aged group (1.27 +/- 0.23 microm s-1). The result indicates that the age-related decrease in contractile speed observed in slow fibres may be the effect of a change in the properties of myosin with age." @default.
• W3147175512 created "2021-04-13" @default.
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• W3147175512 date "1999-12-01" @default.
• W3147175512 modified "2023-10-15" @default.
• W3147175512 title "Control of muscle fibre size: a crucial factor in ageing" @default.
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• W3147175512 doi "https://doi.org/10.1046/j.1365-201x.1999.00619.x" @default.
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