Matches in SemOpenAlex for { <https://semopenalex.org/work/W3147206188> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3147206188 endingPage "985" @default.
- W3147206188 startingPage "978" @default.
- W3147206188 abstract "Traumatic brain injury causes gene expression changes in different brain regions. Occurrence and development of traumatic brain injury are closely related, involving expression of three factors, namely cyclooxygenase-2, glutamate receptor-2, and platelet activating factor receptor. However, little is known about the correlation of these three factors and brain neuronal injury. In this study, primary cultured rat hippocampal neurons were subjected to fluid percussion injury according to Scott’s method, with some modifications. RT-PCR and semi-quantitative immunocytochemical staining was used to measure the expression levels of cyclooxygenase-2, glutamate receptor-2, and platelet activating factor receptor. Our results found that cyclooxygenase-2 expression were firstly increased post-injury, and then decreased. Both mRNA and protein expression levels reached peaks at 8 and 12 hours post-injury, respectively. Similar sequential changes in glutamate receptor 2 were observed, with highest levels mRNA and protein expression at 8 and 12 hours post-injury respectively. On the contrary, the expressions of platelet activating factor receptor were firstly decreased post-injury, and then increased. Both mRNA and protein expression levels reached the lowest levels at 8 and 12 hours post-injury, respectively. Totally, our findings suggest that these three factors are involved in occurrence and development of hippocampal neuronal injury." @default.
- W3147206188 created "2021-04-13" @default.
- W3147206188 creator A5001978013 @default.
- W3147206188 creator A5002097670 @default.
- W3147206188 creator A5008501506 @default.
- W3147206188 creator A5030626459 @default.
- W3147206188 creator A5033179339 @default.
- W3147206188 creator A5041292258 @default.
- W3147206188 creator A5053780153 @default.
- W3147206188 creator A5066634075 @default.
- W3147206188 creator A5071807848 @default.
- W3147206188 date "2014-01-01" @default.
- W3147206188 modified "2023-09-26" @default.
- W3147206188 title "Sequential expression of cyclooxygenase-2, glutamate receptor-2, and platelet activating factor receptor in rat hippocampal neurons after fluid percussion injury" @default.
- W3147206188 hasPublicationYear "2014" @default.
- W3147206188 type Work @default.
- W3147206188 sameAs 3147206188 @default.
- W3147206188 citedByCount "0" @default.
- W3147206188 crossrefType "journal-article" @default.
- W3147206188 hasAuthorship W3147206188A5001978013 @default.
- W3147206188 hasAuthorship W3147206188A5002097670 @default.
- W3147206188 hasAuthorship W3147206188A5008501506 @default.
- W3147206188 hasAuthorship W3147206188A5030626459 @default.
- W3147206188 hasAuthorship W3147206188A5033179339 @default.
- W3147206188 hasAuthorship W3147206188A5041292258 @default.
- W3147206188 hasAuthorship W3147206188A5053780153 @default.
- W3147206188 hasAuthorship W3147206188A5066634075 @default.
- W3147206188 hasAuthorship W3147206188A5071807848 @default.
- W3147206188 hasConcept C104317684 @default.
- W3147206188 hasConcept C105580179 @default.
- W3147206188 hasConcept C126322002 @default.
- W3147206188 hasConcept C134018914 @default.
- W3147206188 hasConcept C148762608 @default.
- W3147206188 hasConcept C170493617 @default.
- W3147206188 hasConcept C181199279 @default.
- W3147206188 hasConcept C185592680 @default.
- W3147206188 hasConcept C2776885963 @default.
- W3147206188 hasConcept C2779020240 @default.
- W3147206188 hasConcept C2779689624 @default.
- W3147206188 hasConcept C2780955469 @default.
- W3147206188 hasConcept C2781161787 @default.
- W3147206188 hasConcept C55493867 @default.
- W3147206188 hasConcept C61174792 @default.
- W3147206188 hasConcept C67018056 @default.
- W3147206188 hasConcept C71924100 @default.
- W3147206188 hasConcept C86803240 @default.
- W3147206188 hasConceptScore W3147206188C104317684 @default.
- W3147206188 hasConceptScore W3147206188C105580179 @default.
- W3147206188 hasConceptScore W3147206188C126322002 @default.
- W3147206188 hasConceptScore W3147206188C134018914 @default.
- W3147206188 hasConceptScore W3147206188C148762608 @default.
- W3147206188 hasConceptScore W3147206188C170493617 @default.
- W3147206188 hasConceptScore W3147206188C181199279 @default.
- W3147206188 hasConceptScore W3147206188C185592680 @default.
- W3147206188 hasConceptScore W3147206188C2776885963 @default.
- W3147206188 hasConceptScore W3147206188C2779020240 @default.
- W3147206188 hasConceptScore W3147206188C2779689624 @default.
- W3147206188 hasConceptScore W3147206188C2780955469 @default.
- W3147206188 hasConceptScore W3147206188C2781161787 @default.
- W3147206188 hasConceptScore W3147206188C55493867 @default.
- W3147206188 hasConceptScore W3147206188C61174792 @default.
- W3147206188 hasConceptScore W3147206188C67018056 @default.
- W3147206188 hasConceptScore W3147206188C71924100 @default.
- W3147206188 hasConceptScore W3147206188C86803240 @default.
- W3147206188 hasIssue "9" @default.
- W3147206188 hasLocation W31472061881 @default.
- W3147206188 hasOpenAccess W3147206188 @default.
- W3147206188 hasPrimaryLocation W31472061881 @default.
- W3147206188 hasRelatedWork W1993213847 @default.
- W3147206188 hasRelatedWork W1998704336 @default.
- W3147206188 hasRelatedWork W2010576546 @default.
- W3147206188 hasRelatedWork W2022028909 @default.
- W3147206188 hasRelatedWork W2044336029 @default.
- W3147206188 hasRelatedWork W2047080646 @default.
- W3147206188 hasRelatedWork W2139798719 @default.
- W3147206188 hasRelatedWork W2267123123 @default.
- W3147206188 hasRelatedWork W2356765827 @default.
- W3147206188 hasRelatedWork W2365639626 @default.
- W3147206188 hasRelatedWork W2385582625 @default.
- W3147206188 hasRelatedWork W2387672138 @default.
- W3147206188 hasRelatedWork W2393648550 @default.
- W3147206188 hasRelatedWork W2803469943 @default.
- W3147206188 hasRelatedWork W2964919039 @default.
- W3147206188 hasRelatedWork W3014748893 @default.
- W3147206188 hasRelatedWork W3029777641 @default.
- W3147206188 hasRelatedWork W3031049224 @default.
- W3147206188 hasRelatedWork W3147346833 @default.
- W3147206188 hasRelatedWork W3111478455 @default.
- W3147206188 hasVolume "9" @default.
- W3147206188 isParatext "false" @default.
- W3147206188 isRetracted "false" @default.
- W3147206188 magId "3147206188" @default.
- W3147206188 workType "article" @default.