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- W3147243208 abstract "An electrochemiluminescence(ECL) sensor based on the use of Nepem-105D perfluorinated ion exchange solution to form the ion exchange membrane on the surface of platinum electrode for immobilization of Ru(bpy)32+ has been developed.A new method was designed combined microdialysis sampling technology and ECL sensor for on-line study of the interactions between ciprofloxacin and bovine serum albumin(BSA).Under the optimized experimental conditions the relative ECL intensity is proportional with ciprofloxacin concentration in the range of 3.0×10-8-3.0×10-5 mol/L with a detection limit of 1.0×10-8 mol/L.The association constant of compound of ciprofloxacin and BSA and the number of the binding sites with Scatchard analysis are 3.51×104 L/mol and 1.49,respectively.The results show that the novel method can provide a fast and simple technique for the study of drug-protein interaction." @default.
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- W3147243208 date "2012-01-01" @default.
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- W3147243208 title "Immobilized Ru(bpy)32��Electrochemiluminescence Coupled with Microdialysis Sampling for On-line Studying Drug-Protein Interaction" @default.
- W3147243208 doi "https://doi.org/10.3724/sp.j.1096.2012.10638" @default.
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