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• W3147267387 abstract "Fungal keratitis is a stubborn fungal infection that is widespread worldwide. It can even affect the health and life of a patient. At present, natamycin (NAT) is the first-line drug in the treatment of fungal keratitis, despite its disadvantages of clinical use, such as low drug bioavailability and poor water solubility. Herein, inspired by the adhesion properties of chitosan and its excellent drug loading and antifungal properties, we designed simple natamycin-chitosan nanoparticles (NAT-NPs) to investigate the feasibility of chitosan with NAT for eye treatment. Results showed that the NAT-NPs increased the antifungal effect of NAT due to the antifungal feature of chitosan NPs. Therefore, NAT-NPs are expected to become potential candidates for the treatment of fungal keratitis due to their high bacteriostasis." @default.
• W3147267387 created "2021-04-13" @default.
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• W3147267387 date "2021-04-03" @default.
• W3147267387 modified "2023-10-16" @default.
• W3147267387 title "Chitosan Nanoparticles to Enhance the Inhibitory Effect of Natamycin on Candida albicans" @default.
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• W3147267387 doi "https://doi.org/10.1155/2021/6644567" @default.
• W3147267387 hasPublicationYear "2021" @default.
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