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- W3147367718 abstract "Objective : To study the relationship between cerebral ischemia and synapse, looking for a new method for studying the brain plasticity after cerebral ischemia. Methods : Cerebral ischemia was induced by permanently occluding the distal middle cerebral artery in healthy SD rats, and electronic microscope was used. Results : After cerebral ischemi-a, the number of the synaptic terminals decreased and the synaptic structure was damaged; the amount of synaptic vesicles were decreased; the cristae of mitochondria were broken, dissolved and disappeared. Presynaptic and postsynaptic membrane became unclear; the outline of presynaptic element was irregular. Fourty-eight hours after ischemia, synaptic vesicles decreased so much that some disappeared. The mitochondria had vacuolar degeneration and sometimes disappeared. The presynaptic and postsynaptic membrane were damaged so seriously that the typical synaptic structure did not exist. Conclusion : After cerebral ischemia, the number of the synaptic terminals decrease and the synaptic structure are dam-" @default.
- W3147367718 created "2021-04-13" @default.
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- W3147367718 date "2003-01-01" @default.
- W3147367718 modified "2023-10-13" @default.
- W3147367718 title "Ultrastructural changes of synapse following focal cerebral ischemia in rats" @default.
- W3147367718 hasPublicationYear "2003" @default.
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