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- W3147397404 abstract "The chemical constituents of sponge Xestospongia testudinaria from the South China Sea were investigated by bioassay-guided fractionation.Eight compounds were isolated from 95% ethanolic extract by repeated column chromatography on silica gel and Sephadex LH-20,and preparative-HPLC.By means of spectroscopic data including NMR and MS,their structures were elucidated as E-9,17-octadecadiene-5,7-diynoic acid-18,18-dibromo-methyl ester(1),E-9,17-octadecadiene-5,7-diynoic acid-18,18-dibromo-ethyl ester(2),ergosta-5,7,22-trien-3-ol(3),ergosta-4,6,8(14),22-tetraen-3-one(4),cholest-4-en-3-one(5),1H-indole-3-carboxaldehyde(6),1H-indole-3-carboxylic acid(7) and 1H-indole-5-carboxaldehyde(8).Compounds 2-5 and 8 were reported from genus Xestospongia for the first time.Moreover,compound 1 showed potent cytotoxicity towards tumor cell lines HCT116 and A549." @default.
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- W3147397404 date "2011-01-01" @default.
- W3147397404 modified "2023-09-23" @default.
- W3147397404 title "Chemical Constituents of Sponge Xestospongia testudinaria from the South China Sea" @default.
- W3147397404 hasPublicationYear "2011" @default.
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