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• W3147430304 abstract "Anorectal malformation (ARM) is a group of significant birth defects with geographic variation in inci- dence, individual phenotypes and regional geographic subtypes occurring in approximately 1:5,000 live births. Anorectal atresia with gross terminal colonic distension in the presence of an absent anal canal has also been known as 'pouch colon' which is mainly associated with the Indian subcontinent. Its prevalence is unknown but it is rare, possibly representing a fraction of 1 % of ARM. The problem seems to revolve around the gross terminal dis- tension of the distal pouch which remains a significant surgical challenge to surgeons resulting in poorer postop- erative continence in many instances. Aim This study set out to collate data on ARM patients with gross terminal distension of the distal pouch from Africa to evaluate its epidemiology and outcome in African patients. Methods Fifteen African paediatric surgical centres (7 South African and 8 African centres) were polled on the occurrence of anorectal atresia with gross terminal disten- sion of the terminal bowel, an ARM variant. Data included ethnic group, age, gender as well as the anatomical pathology, classification and presence or absence of asso- ciated anomalies. Results Of 12 respondents, 8 (67 %) responded and suf- ficient data to classify and analyse were obtained from six of the eight positive replies (7 new cases). Abdominal X-ray showed a grossly dilated terminal portion of the colon in the presence of an imperforate anus. A colovesical fistula was observed in four (three males and one female cloaca). Three were associated with a colonic atresia, of which two were in the transverse colon and one in the sigmoid colon. Surgical corrective procedures were carried out in six, but one patient, with a cloaca, died prior to surgical correction. Conclusions In this survey of 15 African centres, we have attempted to document the occurrence and presentation of anorectal atresia with gross terminal distension in Africa and report seven additional new cases. A possible associ- ation with associated conditions like colonic atresia requires further investigation." @default.
• W3147430304 created "2021-04-13" @default.
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• W3147430304 date "2013-01-01" @default.
• W3147430304 modified "2023-09-27" @default.
• W3147430304 title "Anorectal atresia with gross terminal colonic distension in Africa" @default.
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