Matches in SemOpenAlex for { <https://semopenalex.org/work/W3147644634> ?p ?o ?g. }
- W3147644634 endingPage "537" @default.
- W3147644634 startingPage "528" @default.
- W3147644634 abstract "Environmental exposure to sodium fluoride (NaF) compounds is a worldwide health concern. Epigallocatechin gallate (EGCG) is a green tea catechin found in a variety of green tea preparations. The intention of this study was to investigate the hepatoprotective role of EGCG in NaF-intoxicated rats. Rats were orally treated with NaF alone (25 mg·(kg body mass) −1 ·day −1 ) or plus EGCG at different doses (20, 40, and 80 mg·(kg body mass) −1 ·day −1 ) for 4 weeks. Hepatotoxicity of NaF was determined by increased levels of serum hepatospecific markers and total bilirubin, along with increased levels of thiobarbituric acid reactive substances, lipid hydroperoxides, protein carbonyl content, and conjugated dienes. The hepatotoxic nature of NaF was further evidenced by the decreased activity of enzymatic and nonenzymatic antioxidant levels in liver. NaF-treated rats also showed increased DNA damage and fragmentation in hepatocytes. Administration of EGCG (40 mg·(kg body mass) −1 ) to NaF-intoxicated rats significantly recuperated the distorted biochemical indices, DNA damage, and pathological changes in the liver tissue. Thus, the results of the present study clearly demonstrate that EGCG has strong free radical scavenging, antioxidant, and antigenotoxic properties that protect against NaF-induced oxidative hepatic injury in rats." @default.
- W3147644634 created "2021-04-13" @default.
- W3147644634 creator A5019962321 @default.
- W3147644634 creator A5044866437 @default.
- W3147644634 date "2013-07-01" @default.
- W3147644634 modified "2023-10-18" @default.
- W3147644634 title "Epigallocatechin gallate effectively ameliorates fluoride-induced oxidative stress and DNA damage in the liver of rats" @default.
- W3147644634 cites W1554188337 @default.
- W3147644634 cites W1559601107 @default.
- W3147644634 cites W1567614586 @default.
- W3147644634 cites W1581414347 @default.
- W3147644634 cites W1775749144 @default.
- W3147644634 cites W1981003011 @default.
- W3147644634 cites W1985986126 @default.
- W3147644634 cites W1986464172 @default.
- W3147644634 cites W1992242706 @default.
- W3147644634 cites W1995382021 @default.
- W3147644634 cites W1997830446 @default.
- W3147644634 cites W2000957660 @default.
- W3147644634 cites W2002801265 @default.
- W3147644634 cites W2004054968 @default.
- W3147644634 cites W2006370393 @default.
- W3147644634 cites W2010351226 @default.
- W3147644634 cites W2013517575 @default.
- W3147644634 cites W2020761777 @default.
- W3147644634 cites W2024931990 @default.
- W3147644634 cites W2027617131 @default.
- W3147644634 cites W2028437087 @default.
- W3147644634 cites W2039774338 @default.
- W3147644634 cites W2041113024 @default.
- W3147644634 cites W2058113939 @default.
- W3147644634 cites W2060194897 @default.
- W3147644634 cites W2061333433 @default.
- W3147644634 cites W2064645704 @default.
- W3147644634 cites W2069132215 @default.
- W3147644634 cites W2070203955 @default.
- W3147644634 cites W2072161661 @default.
- W3147644634 cites W2079351469 @default.
- W3147644634 cites W2082198711 @default.
- W3147644634 cites W2096795975 @default.
- W3147644634 cites W2113227870 @default.
- W3147644634 cites W2116597521 @default.
- W3147644634 cites W2144841712 @default.
- W3147644634 cites W2153435210 @default.
- W3147644634 cites W2155411288 @default.
- W3147644634 cites W2159481986 @default.
- W3147644634 cites W2160748095 @default.
- W3147644634 cites W2166972288 @default.
- W3147644634 cites W2168987076 @default.
- W3147644634 cites W2313679778 @default.
- W3147644634 cites W2539336881 @default.
- W3147644634 cites W8481089 @default.
- W3147644634 doi "https://doi.org/10.1139/cjpp-2012-0347" @default.
- W3147644634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23826622" @default.
- W3147644634 hasPublicationYear "2013" @default.
- W3147644634 type Work @default.
- W3147644634 sameAs 3147644634 @default.
- W3147644634 citedByCount "46" @default.
- W3147644634 countsByYear W31476446342014 @default.
- W3147644634 countsByYear W31476446342015 @default.
- W3147644634 countsByYear W31476446342016 @default.
- W3147644634 countsByYear W31476446342017 @default.
- W3147644634 countsByYear W31476446342018 @default.
- W3147644634 countsByYear W31476446342019 @default.
- W3147644634 countsByYear W31476446342020 @default.
- W3147644634 countsByYear W31476446342021 @default.
- W3147644634 countsByYear W31476446342022 @default.
- W3147644634 countsByYear W31476446342023 @default.
- W3147644634 crossrefType "journal-article" @default.
- W3147644634 hasAuthorship W3147644634A5019962321 @default.
- W3147644634 hasAuthorship W3147644634A5044866437 @default.
- W3147644634 hasConcept C134018914 @default.
- W3147644634 hasConcept C179104552 @default.
- W3147644634 hasConcept C185592680 @default.
- W3147644634 hasConcept C2776151105 @default.
- W3147644634 hasConcept C2776637226 @default.
- W3147644634 hasConcept C2777056448 @default.
- W3147644634 hasConcept C2777192995 @default.
- W3147644634 hasConcept C2777504301 @default.
- W3147644634 hasConcept C2778004101 @default.
- W3147644634 hasConcept C2779234887 @default.
- W3147644634 hasConcept C2779431889 @default.
- W3147644634 hasConcept C2780162734 @default.
- W3147644634 hasConcept C2780828025 @default.
- W3147644634 hasConcept C2780829032 @default.
- W3147644634 hasConcept C55493867 @default.
- W3147644634 hasConcept C70899900 @default.
- W3147644634 hasConcept C71924100 @default.
- W3147644634 hasConcept C98274493 @default.
- W3147644634 hasConceptScore W3147644634C134018914 @default.
- W3147644634 hasConceptScore W3147644634C179104552 @default.
- W3147644634 hasConceptScore W3147644634C185592680 @default.
- W3147644634 hasConceptScore W3147644634C2776151105 @default.
- W3147644634 hasConceptScore W3147644634C2776637226 @default.
- W3147644634 hasConceptScore W3147644634C2777056448 @default.
- W3147644634 hasConceptScore W3147644634C2777192995 @default.
- W3147644634 hasConceptScore W3147644634C2777504301 @default.
- W3147644634 hasConceptScore W3147644634C2778004101 @default.