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- W3147646912 abstract "Abstract Both the α‐amidoacrylate and 3‐ylideneooxindole frameworks are important in medicinal chemistry because of their associated biological activities. We report a novel approach to accessing α‐amidoacrylates containing a 3‐ylideneoxindole motif through a novel cascade process involving condensation between 3‐fluorooxindoles and α‐iminoacetates followed by elimination of HF. This protocol has a broad substrate scope: N ‐alkyl‐, N ‐aryl‐, N ‐allyl‐, N ‐propargyl 3‐fluorooxindoles and 3‐fluorooxindoles with different substituents on the aromatic rings were all suitable for this reaction. A plausible reaction pathway is also presented." @default.
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- W3147646912 date "2021-04-07" @default.
- W3147646912 modified "2023-09-26" @default.
- W3147646912 title "Synthesis of α‐Amidoacrylates Containing a 3‐Ylideneoxindole Motif" @default.
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- W3147646912 doi "https://doi.org/10.1002/slct.202100578" @default.
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