Matches in SemOpenAlex for { <https://semopenalex.org/work/W3147706670> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3147706670 endingPage "1126" @default.
- W3147706670 startingPage "1119" @default.
- W3147706670 abstract "瞄准：我们执行了这研究在细胞外的调整信号的 kinase/mitogen 上调查人参皂甙 Rg1 的效果激活的蛋白质 kinase (ERK/ MAPK ) 为在 synaptic platicity 上理解它的效果的小径。方法：西方的弄污并且免疫染色被用来在 PC 12 房间和 synaptosomes 检验 ERK1/2， CaMKIIα 和营地反应元素绑定蛋白质(CREB ) 的 phosphorylation。共焦的显微镜学和荧光灯的指示物 Fluo-3 被使用观察细胞内部的钙离子流动。结果：在与 Rg1 孵化的 PC 12 房间和 synaptosomes 的 ERK1/2 的 phosphorylation 在 4 min 被增加并且到达最大值。Rg1 也支持了在上游的钙离子的短暂改进并且激活 CaMKIIot，它在 2 min 到达了最大值。CREB，下游的蛋白质，是在在在与 Rg1 被孵化以后的 PC 12 房间的 8 min 以内的 phosphorylat 编辑。而且， KN93 部分也禁止了 ERK1/2，和 PD98059 的激活部分堵住了 CREB 的 phosphorylation。结论：Rg1 由 CaMKIIα 激活 ERK/MAPK 小径，并且 CREB 的激活依赖于英皇家空军之阶级最低之兵不仅由 Rg1 导致了，它可以在长期的 potentiation 上为 Rg1 的效果提供解释。" @default.
- W3147706670 created "2021-04-13" @default.
- W3147706670 creator A5001870409 @default.
- W3147706670 creator A5001978013 @default.
- W3147706670 creator A5006579524 @default.
- W3147706670 creator A5013538771 @default.
- W3147706670 creator A5035640856 @default.
- W3147706670 creator A5052500563 @default.
- W3147706670 creator A5057065866 @default.
- W3147706670 creator A5060073997 @default.
- W3147706670 creator A5068607867 @default.
- W3147706670 creator A5071512084 @default.
- W3147706670 creator A5080556926 @default.
- W3147706670 date "2008-01-01" @default.
- W3147706670 modified "2023-09-23" @default.
- W3147706670 title "Ginsenoside Rg1 activated CaMKIIα mediated extracellular signal-regulated kinaselmitogen activated protein kinase signaling pathway" @default.
- W3147706670 hasPublicationYear "2008" @default.
- W3147706670 type Work @default.
- W3147706670 sameAs 3147706670 @default.
- W3147706670 citedByCount "0" @default.
- W3147706670 crossrefType "journal-article" @default.
- W3147706670 hasAuthorship W3147706670A5001870409 @default.
- W3147706670 hasAuthorship W3147706670A5001978013 @default.
- W3147706670 hasAuthorship W3147706670A5006579524 @default.
- W3147706670 hasAuthorship W3147706670A5013538771 @default.
- W3147706670 hasAuthorship W3147706670A5035640856 @default.
- W3147706670 hasAuthorship W3147706670A5052500563 @default.
- W3147706670 hasAuthorship W3147706670A5057065866 @default.
- W3147706670 hasAuthorship W3147706670A5060073997 @default.
- W3147706670 hasAuthorship W3147706670A5068607867 @default.
- W3147706670 hasAuthorship W3147706670A5071512084 @default.
- W3147706670 hasAuthorship W3147706670A5080556926 @default.
- W3147706670 hasConcept C104317684 @default.
- W3147706670 hasConcept C11960822 @default.
- W3147706670 hasConcept C1629964 @default.
- W3147706670 hasConcept C170493617 @default.
- W3147706670 hasConcept C184235292 @default.
- W3147706670 hasConcept C185592680 @default.
- W3147706670 hasConcept C195794163 @default.
- W3147706670 hasConcept C25274449 @default.
- W3147706670 hasConcept C55493867 @default.
- W3147706670 hasConcept C57074206 @default.
- W3147706670 hasConcept C62478195 @default.
- W3147706670 hasConcept C86339819 @default.
- W3147706670 hasConcept C86803240 @default.
- W3147706670 hasConcept C90934575 @default.
- W3147706670 hasConcept C95444343 @default.
- W3147706670 hasConcept C97029542 @default.
- W3147706670 hasConceptScore W3147706670C104317684 @default.
- W3147706670 hasConceptScore W3147706670C11960822 @default.
- W3147706670 hasConceptScore W3147706670C1629964 @default.
- W3147706670 hasConceptScore W3147706670C170493617 @default.
- W3147706670 hasConceptScore W3147706670C184235292 @default.
- W3147706670 hasConceptScore W3147706670C185592680 @default.
- W3147706670 hasConceptScore W3147706670C195794163 @default.
- W3147706670 hasConceptScore W3147706670C25274449 @default.
- W3147706670 hasConceptScore W3147706670C55493867 @default.
- W3147706670 hasConceptScore W3147706670C57074206 @default.
- W3147706670 hasConceptScore W3147706670C62478195 @default.
- W3147706670 hasConceptScore W3147706670C86339819 @default.
- W3147706670 hasConceptScore W3147706670C86803240 @default.
- W3147706670 hasConceptScore W3147706670C90934575 @default.
- W3147706670 hasConceptScore W3147706670C95444343 @default.
- W3147706670 hasConceptScore W3147706670C97029542 @default.
- W3147706670 hasIssue "9" @default.
- W3147706670 hasLocation W31477066701 @default.
- W3147706670 hasOpenAccess W3147706670 @default.
- W3147706670 hasPrimaryLocation W31477066701 @default.
- W3147706670 hasRelatedWork W1597117860 @default.
- W3147706670 hasRelatedWork W1902752790 @default.
- W3147706670 hasRelatedWork W1977536374 @default.
- W3147706670 hasRelatedWork W2000712251 @default.
- W3147706670 hasRelatedWork W2004800300 @default.
- W3147706670 hasRelatedWork W2004809817 @default.
- W3147706670 hasRelatedWork W2022051816 @default.
- W3147706670 hasRelatedWork W2032500888 @default.
- W3147706670 hasRelatedWork W2040839305 @default.
- W3147706670 hasRelatedWork W2047566724 @default.
- W3147706670 hasRelatedWork W2048198188 @default.
- W3147706670 hasRelatedWork W2064128197 @default.
- W3147706670 hasRelatedWork W2072989572 @default.
- W3147706670 hasRelatedWork W2079450435 @default.
- W3147706670 hasRelatedWork W2080795141 @default.
- W3147706670 hasRelatedWork W2118368843 @default.
- W3147706670 hasRelatedWork W2198894073 @default.
- W3147706670 hasRelatedWork W2312737930 @default.
- W3147706670 hasRelatedWork W2580267222 @default.
- W3147706670 hasRelatedWork W3144053559 @default.
- W3147706670 hasVolume "29" @default.
- W3147706670 isParatext "false" @default.
- W3147706670 isRetracted "false" @default.
- W3147706670 magId "3147706670" @default.
- W3147706670 workType "article" @default.