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- W3147887930 abstract "目的将在到人的肺的腺癌 A549 房间的内皮细胞层的移植，侵略和粘附上评估组织缺氧的效果。愈合创伤的方法和 Transwell 侵略试金被执行在 A549 房间的移植和侵略上学习组织缺氧的效果，并且 A549 房间被加到人的脐的静脉 endothelial (HUVEC ) 的单层测试能力遵守内皮细胞层。Immunofluorescence 试金和酶记者基因试金也被用来在 E-cadherin， β-catenin，和肌动朊，和组织缺氧可诱导的 factor-1 (HIF-1 ) 依赖者的分发上评估组织缺氧的效果抄写分别地。结果组织缺氧便于 A549 细胞移行，侵略，和 A549 cell-endothelial 房间粘附，并且调制了分发 E-cadherin 和 β-catenin，和肌动朊细胞骨架重新整理，和起来调整的 HIF-1-dependent 在 A549 房间的记者基因表示。由组织缺氧的内皮细胞层上的 A549 细胞移行，侵略，和粘附的结论提升可能通过它的起来调整的 HIF-1-dependent 基因表示被调制，它然后导致了再分配 E-cadherin 和 β-catenin，和肌动朊细胞骨架重组。" @default.
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- W3147887930 date "2008-01-01" @default.
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- W3147887930 title "Effect of hypoxia on migration, invasion and adhesion to endothelium of human pulmonary adenocarcinoma A549 cells" @default.
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