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- W3147889041 abstract "Objective To find out the relationship of lipid peroxidation and antioxidative level with liver injury of workers occopationally exposed to DMF.Methods To select 136 workers occupationally exposed to DMF as the exposure group and 30 healthy blood doners without any exposure to chemical toxicants and other hazards as the control group.According to the liver function,the exposure group were divided into liver injury group and normal exposure group.According to the concentration of DMF,the normal exposure group were further divided into low concentration group and high concentration group.The level of MDA and the activities GSH-Px and SOD in serum were determined in various groups.Results The level of MDA and the activities of SOD in various exposure groups were signifcantly higher than that of the control group,and it was high in the liver injury group.The GSH-Px activities in the high concentration group and liver injury group were significantly lower than that of the control group.The GSH-Px activities in the low concentration was significantly higher than that of the control group.The level of MDA and GSH-Px activities between liver injury group and normal exposure group had significant difference.Conclusion High concentration of DMF exposure could decrsease the ability to delete the reactive oxygen species and induce liver injure.It was sense that antioxidant was used to provent and care DMF toxicosis." @default.
- W3147889041 created "2021-04-13" @default.
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- W3147889041 date "2007-01-01" @default.
- W3147889041 modified "2023-09-24" @default.
- W3147889041 title "Relationship between liver injury and lipid peroxidation in workers exposed to N,N-dimethylformamide" @default.
- W3147889041 hasPublicationYear "2007" @default.
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