Matches in SemOpenAlex for { <https://semopenalex.org/work/W3147934251> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W3147934251 endingPage "1057" @default.
- W3147934251 startingPage "1042" @default.
- W3147934251 abstract "Effective utilization of xylose is a basis for economic production of biofuels or chemicals from lignocellulose biomass. Over the past 30 years, through metabolic engineering, evolutionary engineering and other strategies, the metabolic capacity of xylose of the traditional ethanol-producing microorganism Saccharomyces cerevisiae has been significantly improved. In recent years, the reported results showed that the transcriptome and metabolome profiles between xylose and glucose metabolism existed significant difference in recombinant yeast strains. Compared with glucose, the overall process of xylose metabolism exhibits Crabtree-negative characteristics, including the limited glycolytic pathway activity, which reduces the metabolic flux of pyruvate to ethanol, and the enhanced cytosolic acetyl-CoA synthesis and respiratory energy metabolism. These traits are helpful to achieve efficient synthesis of downstream products using pyruvate or acetyl-CoA as precursors. This review provides a detailed overview on the modification and optimization of xylose metabolic pathways in S. cerevisiae, the characteristics of xylose metabolism, and the construction of cell factories for production of chemicals using xylose as a carbon source. Meanwhile, the existed difficulties and challenges, and future studies on biosynthesis of bulk chemicals using xylose as an important carbon source are proposed." @default.
- W3147934251 created "2021-04-13" @default.
- W3147934251 creator A5013765598 @default.
- W3147934251 creator A5021169746 @default.
- W3147934251 creator A5045204358 @default.
- W3147934251 creator A5071389166 @default.
- W3147934251 creator A5086689827 @default.
- W3147934251 date "2021-03-25" @default.
- W3147934251 modified "2023-09-27" @default.
- W3147934251 title "Progress in studies on production of chemicals from xylose by Saccharomyces cerevisiae" @default.
- W3147934251 doi "https://doi.org/10.13345/j.cjb.200708" @default.
- W3147934251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33783167" @default.
- W3147934251 hasPublicationYear "2021" @default.
- W3147934251 type Work @default.
- W3147934251 sameAs 3147934251 @default.
- W3147934251 citedByCount "0" @default.
- W3147934251 crossrefType "journal-article" @default.
- W3147934251 hasAuthorship W3147934251A5013765598 @default.
- W3147934251 hasAuthorship W3147934251A5021169746 @default.
- W3147934251 hasAuthorship W3147934251A5045204358 @default.
- W3147934251 hasAuthorship W3147934251A5071389166 @default.
- W3147934251 hasAuthorship W3147934251A5086689827 @default.
- W3147934251 hasConcept C100544194 @default.
- W3147934251 hasConcept C115540264 @default.
- W3147934251 hasConcept C135870905 @default.
- W3147934251 hasConcept C160941953 @default.
- W3147934251 hasConcept C181199279 @default.
- W3147934251 hasConcept C185592680 @default.
- W3147934251 hasConcept C192989942 @default.
- W3147934251 hasConcept C2777477808 @default.
- W3147934251 hasConcept C2777576037 @default.
- W3147934251 hasConcept C2779222958 @default.
- W3147934251 hasConcept C2780294150 @default.
- W3147934251 hasConcept C2781135521 @default.
- W3147934251 hasConcept C55493867 @default.
- W3147934251 hasConcept C62231903 @default.
- W3147934251 hasConcept C6350086 @default.
- W3147934251 hasConcept C65183824 @default.
- W3147934251 hasConcept C6557445 @default.
- W3147934251 hasConcept C86803240 @default.
- W3147934251 hasConceptScore W3147934251C100544194 @default.
- W3147934251 hasConceptScore W3147934251C115540264 @default.
- W3147934251 hasConceptScore W3147934251C135870905 @default.
- W3147934251 hasConceptScore W3147934251C160941953 @default.
- W3147934251 hasConceptScore W3147934251C181199279 @default.
- W3147934251 hasConceptScore W3147934251C185592680 @default.
- W3147934251 hasConceptScore W3147934251C192989942 @default.
- W3147934251 hasConceptScore W3147934251C2777477808 @default.
- W3147934251 hasConceptScore W3147934251C2777576037 @default.
- W3147934251 hasConceptScore W3147934251C2779222958 @default.
- W3147934251 hasConceptScore W3147934251C2780294150 @default.
- W3147934251 hasConceptScore W3147934251C2781135521 @default.
- W3147934251 hasConceptScore W3147934251C55493867 @default.
- W3147934251 hasConceptScore W3147934251C62231903 @default.
- W3147934251 hasConceptScore W3147934251C6350086 @default.
- W3147934251 hasConceptScore W3147934251C65183824 @default.
- W3147934251 hasConceptScore W3147934251C6557445 @default.
- W3147934251 hasConceptScore W3147934251C86803240 @default.
- W3147934251 hasIssue "3" @default.
- W3147934251 hasLocation W31479342511 @default.
- W3147934251 hasOpenAccess W3147934251 @default.
- W3147934251 hasPrimaryLocation W31479342511 @default.
- W3147934251 hasRelatedWork W1173634030 @default.
- W3147934251 hasRelatedWork W1896895429 @default.
- W3147934251 hasRelatedWork W1908662736 @default.
- W3147934251 hasRelatedWork W1973488815 @default.
- W3147934251 hasRelatedWork W2012464139 @default.
- W3147934251 hasRelatedWork W2039522748 @default.
- W3147934251 hasRelatedWork W2060718895 @default.
- W3147934251 hasRelatedWork W2097790673 @default.
- W3147934251 hasRelatedWork W2153504900 @default.
- W3147934251 hasRelatedWork W2170563139 @default.
- W3147934251 hasRelatedWork W2397674976 @default.
- W3147934251 hasRelatedWork W2482791848 @default.
- W3147934251 hasRelatedWork W2730800840 @default.
- W3147934251 hasRelatedWork W2953576540 @default.
- W3147934251 hasRelatedWork W2982018316 @default.
- W3147934251 hasRelatedWork W3122370192 @default.
- W3147934251 hasRelatedWork W3158435957 @default.
- W3147934251 hasRelatedWork W3202653026 @default.
- W3147934251 hasRelatedWork W3204357917 @default.
- W3147934251 hasRelatedWork W93910327 @default.
- W3147934251 hasVolume "37" @default.
- W3147934251 isParatext "false" @default.
- W3147934251 isRetracted "false" @default.
- W3147934251 magId "3147934251" @default.
- W3147934251 workType "article" @default.