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• W3147995833 endingPage "12287" @default.
• W3147995833 startingPage "12254" @default.
• W3147995833 abstract "Isoquinoline alkaloids are a large group of natural products in which 1,2,3,4-tetrahydroisoquinolines (THIQ) form an important class. THIQ based natural and synthetic compounds exert diverse biological activities against various infective pathogens and neurodegenerative disorders. Due to these reasons, the THIQ heterocyclic scaffold has garnered a lot of attention in the scientific community which has resulted in the development of novel THIQ analogs with potent biological activity. The present review provides a much-needed update on the biological potential of THIQ analogs, their structural-activity relationship (SAR), and their mechanism of action. In addition, a note on commonly used synthetic strategies for constructing the core scaffold has also been discussed." @default.
• W3147995833 created "2021-04-13" @default.
• W3147995833 creator A5011635792 @default.
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• W3147995833 creator A5048793140 @default.
• W3147995833 creator A5078153016 @default.
• W3147995833 date "2021-01-01" @default.
• W3147995833 modified "2023-10-12" @default.
• W3147995833 title "Medicinal chemistry perspectives of 1,2,3,4-tetrahydroisoquinoline analogs – biological activities and SAR studies" @default.
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