FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3148031959> ?p ?o ?g. }

• W3148031959 abstract "Previous studies have suggested that insulin- like growth factor binding protein-3 (IGFBP-3) acts as a tumor suppressor in human esophageal squamous cell carcinoma (ESCC). The present study was designed to investigate the clinical and prognostic significance of IG- FBP-3 in ESCC patients. In this study, IGFBP-3 was detected by immunohistochemistry (IHC) in paraffin- embedded tissues from 110 ESCC patients, of which 110 were from primary cancer sites and 56 from matched adjacent non-malignant sites. Differences in IGFBP-3 expression and clinical characteristics were compared by v 2 test. Correlations between prognostic outcomes and with IGFBP-3 expression were investigated using Kaplan-Me- ier analysis and the Cox proportional hazards model. Among adjacent non-malignant tissues, 83.9% of individ- ual tissue staining was scored as either high for IGFBP-3. However, among ESCC cases, only 51.8% of the cancer tissues were scored as high IGFBP-3 expression. In addi- tion, IGFBP-3 expression inversely correlated with patho- logical classification (P 0.05 for T, N, and M classifications) and clinical staging (P = 0.006). Further- more, patients with higher levels of IGFBP-3 had prolonged overall survival (P 0.001). In conclusion, reduced IGFBP-3 expression may be a risk factor for advanced clinicopathological classification and poor patient survival. These findings suggest that IGFBP-3 may serve as a useful marker for the prognostic evaluation of ESCC patients." @default.
• W3148031959 created "2021-04-13" @default.
• W3148031959 creator A5030876746 @default.
• W3148031959 creator A5085733223 @default.
• W3148031959 date "2012-01-01" @default.
• W3148031959 modified "2023-09-27" @default.
• W3148031959 title "Low expression of IGFBP-3 predicts poor prognosis in patients with esophageal squamous cell carcinoma" @default.
• W3148031959 cites W1577570013 @default.
• W3148031959 cites W1761825801 @default.
• W3148031959 cites W1965477604 @default.
• W3148031959 cites W1971398781 @default.
• W3148031959 cites W1974433743 @default.
• W3148031959 cites W1974631544 @default.
• W3148031959 cites W1984529564 @default.
• W3148031959 cites W1985215669 @default.
• W3148031959 cites W1987381753 @default.
• W3148031959 cites W1998893299 @default.
• W3148031959 cites W2003313289 @default.
• W3148031959 cites W2012505775 @default.
• W3148031959 cites W2013340161 @default.
• W3148031959 cites W2018089794 @default.
• W3148031959 cites W2024410864 @default.
• W3148031959 cites W2035190528 @default.
• W3148031959 cites W2054823635 @default.
• W3148031959 cites W2062494807 @default.
• W3148031959 cites W2068989573 @default.
• W3148031959 cites W2077956417 @default.
• W3148031959 cites W2078902093 @default.
• W3148031959 cites W2082792838 @default.
• W3148031959 cites W2098409179 @default.
• W3148031959 cites W2098618859 @default.
• W3148031959 cites W2111365053 @default.
• W3148031959 cites W2115850999 @default.
• W3148031959 cites W2130377526 @default.
• W3148031959 cites W2133463872 @default.
• W3148031959 cites W2140491527 @default.
• W3148031959 cites W2144678487 @default.
• W3148031959 cites W2159030309 @default.
• W3148031959 cites W2398281943 @default.
• W3148031959 cites W3143514327 @default.
• W3148031959 hasPublicationYear "2012" @default.
• W3148031959 type Work @default.
• W3148031959 sameAs 3148031959 @default.
• W3148031959 citedByCount "0" @default.
• W3148031959 crossrefType "journal-article" @default.
• W3148031959 hasAuthorship W3148031959A5030876746 @default.
• W3148031959 hasAuthorship W3148031959A5085733223 @default.
• W3148031959 hasConcept C10515644 @default.
• W3148031959 hasConcept C121608353 @default.
• W3148031959 hasConcept C126322002 @default.
• W3148031959 hasConcept C142724271 @default.
• W3148031959 hasConcept C143998085 @default.
• W3148031959 hasConcept C170493617 @default.
• W3148031959 hasConcept C204232928 @default.
• W3148031959 hasConcept C2775960820 @default.
• W3148031959 hasConcept C2777546739 @default.
• W3148031959 hasConcept C2779742542 @default.
• W3148031959 hasConcept C2780378035 @default.
• W3148031959 hasConcept C2780689927 @default.
• W3148031959 hasConcept C2994415158 @default.
• W3148031959 hasConcept C50382708 @default.
• W3148031959 hasConcept C63363279 @default.
• W3148031959 hasConcept C71924100 @default.
• W3148031959 hasConceptScore W3148031959C10515644 @default.
• W3148031959 hasConceptScore W3148031959C121608353 @default.
• W3148031959 hasConceptScore W3148031959C126322002 @default.
• W3148031959 hasConceptScore W3148031959C142724271 @default.
• W3148031959 hasConceptScore W3148031959C143998085 @default.
• W3148031959 hasConceptScore W3148031959C170493617 @default.
• W3148031959 hasConceptScore W3148031959C204232928 @default.
• W3148031959 hasConceptScore W3148031959C2775960820 @default.
• W3148031959 hasConceptScore W3148031959C2777546739 @default.
• W3148031959 hasConceptScore W3148031959C2779742542 @default.
• W3148031959 hasConceptScore W3148031959C2780378035 @default.
• W3148031959 hasConceptScore W3148031959C2780689927 @default.
• W3148031959 hasConceptScore W3148031959C2994415158 @default.
• W3148031959 hasConceptScore W3148031959C50382708 @default.
• W3148031959 hasConceptScore W3148031959C63363279 @default.
• W3148031959 hasConceptScore W3148031959C71924100 @default.
• W3148031959 hasLocation W31480319591 @default.
• W3148031959 hasOpenAccess W3148031959 @default.
• W3148031959 hasPrimaryLocation W31480319591 @default.
• W3148031959 hasRelatedWork W1915778718 @default.
• W3148031959 hasRelatedWork W2041523782 @default.
• W3148031959 hasRelatedWork W2048670247 @default.
• W3148031959 hasRelatedWork W2068611558 @default.
• W3148031959 hasRelatedWork W2171136249 @default.
• W3148031959 hasRelatedWork W2231564396 @default.
• W3148031959 hasRelatedWork W2278693810 @default.
• W3148031959 hasRelatedWork W2328239871 @default.
• W3148031959 hasRelatedWork W2364940802 @default.
• W3148031959 hasRelatedWork W2367229362 @default.
• W3148031959 hasRelatedWork W2387918560 @default.
• W3148031959 hasRelatedWork W2412014339 @default.
• W3148031959 hasRelatedWork W2530986481 @default.
• W3148031959 hasRelatedWork W2600666233 @default.
• W3148031959 hasRelatedWork W2605289005 @default.
• W3148031959 hasRelatedWork W2739179087 @default.
• W3148031959 hasRelatedWork W2793137333 @default.
• W3148031959 hasRelatedWork W2980352905 @default.

• next