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- W3148050933 abstract "Objective To monitor the bacteria resistance in burn patients. Methods Disk susceptibility tests were performed and interpreted according to the NCCLS criteria.Four kinds of the third generation cephalosporins extendedspectrum lactamase produced by multiresistant of P.aeruginosa and5BX K.Pneumoniae strains were detected after 20 g of sulbactam was added respectively, in contrast to no sulbactam. Results 227 strains were isolated from burn patients. 195 strains (86%) were gramnegative bacteria. Disk susceptibility showed various bacteria had high antibiotic resistance and multiresistant rate. S.aureus5BZ was only susceptible to vancomycin, its resistant rate to imipenem was 19%. P.aeruginosa was only susceptible to polymyxinB, its resistant rate to ceftazidime was 20%.However, after stop using ceftaxidime two years, the susceptibility to gramnegative bacteria recovered. The resistant rate of ceftazidime to P.aeruginosa, E.coli, K.pneumoniaeZ were decreased respectively. The resistance to quinolones was increased. The resitant rate of ciprofloxacin to P.aeruginosa,K.pneumoniaeBZ was increased respectively. After 20 g sulbactam added to cephalosporins drug disks, the primary susceptibility of ceftazidime to P.aeruginosa and K.pneumoniae recovered, and the antibiotic was better than the other cephalosporins. Conclusions It is important to monitor the bacteriology in burn patients at all time, and understand the changing pattern of bacterial flora, antibiotic susceptibility and bacterial strains spreading in burn ward.Extendedspectrum lactamases is the cause of resistance.After sulbactam added to the third generation of cephalosporins, the lactamases were inhibited, and the susceptibility of antibiotics to bacteria were increased and ceftazidime was prior to others." @default.
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- W3148050933 date "1999-01-01" @default.
- W3148050933 modified "2023-09-26" @default.
- W3148050933 title "Monitoring of bacteria resistance in burn patients" @default.
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