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- W3148227992 abstract "The atherogenicity of dietary peanut oil (PO) was examined in cynomolgus monkeys fed semipurified diets for 15 months. Four groups of six monkeys were fed diets containing 0.22 mg/kcal (0.1%) cholesterol and 0%, 5%, 10%, or 20% PO. An additional group was fed 2.0% cholesterol and 20% PO to serve as a literature control. Increasing the concentration of PO in the diet was associated with significant decreases in total plasma cholesterol (p less than 0.05) and the total/HDL cholesterol ratio (p less than 0.05) and an increase in the terminal HDL cholesterol concentration (p less than 0.05). Intimal thickness and composition were determined from cross sections of the thoracic aorta and the iliac and coronary arteries. Increasing dietary PO was associated with decreases in thickness (p less than 0.005), lipid (p less than 0.001), and smooth muscle cells (p less than 0.005) in the aortic intima. Aortic intimal lipid was positively correlated with the ratio of total to HDL cholesterol (r2 = 0.78, p less than 0.0..." @default.
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- W3148227992 date "1986-01-01" @default.
- W3148227992 modified "2023-09-22" @default.
- W3148227992 title "Peanut oil reduces diet-induced atherosclerosis in cynomolgus monkeys." @default.
- W3148227992 hasPublicationYear "1986" @default.
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