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- W3148338977 abstract "在细胞色素 c 的版本和 Bcl-2 的表情上调查杂种狗枯茗的效果的目的， Bax，坏， Bcl-xL， caspase-3， poly 自动数据处理核糖聚合酶(PARP ) ，和 HT-29 房间的 survivin。方法：HT-29 房间为 24 h 与杂种狗枯茗(0 ∼80 μmol/L ) 被对待。从线粒体和 apoptosis 相关的蛋白质 Bax， Bcl-2， Bcl-xL， Bad， caspase-3， PARP，和 survivin 的细胞色素 c 的版本被西方的污点分析决定，他们由反向的 transcriptase 聚合酶的 mRNA 表情锁住反应(RT-PCR ) 。结果 Curcumin 显著地导致了生长抑制和 HT-29 房间的 apoptosis。在 Bcl-2， Bcl-xL 和 survivin 的表情的减少在暴露以后被观察到 10 ∼80 μmol/L 杂种狗枯茗，当 Bax 和 Bad 的层次在对待 curcumin 的房间增加了时。Curcumin 也以一种剂量依赖者方式导致了细胞色素 c， caspase-3 的激活，和 PARP 的劈开的版本。结论这些数据建议那杂种狗枯茗经由调停线粒体的小径可能导致了 HT-29 房间 apoptosis。" @default.
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- W3148338977 date "2009-01-01" @default.
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- W3148338977 title "Curcumin induces apoptosis through the mitochondria-mediated apoptotic pathway in HT-29 cells" @default.
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