Matches in SemOpenAlex for { <https://semopenalex.org/work/W3148399466> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3148399466 endingPage "2089" @default.
- W3148399466 startingPage "2089" @default.
- W3148399466 abstract "The aim of the study was to create a mathematical model useful for monitoring the release of bioactive aldehydes covalently bonded to the chitosan by reversible imine linkage, considered as a polymer–drug system. For this purpose, two hydrogels were prepared by the acid condensation reaction of chitosan with the antifungal 2-formyl-phenyl-boronic acid and their particularities; influencing the release of the antifungal aldehyde by shifting the imination equilibrium to the reagents was considered, i.e., the supramolecular nature of the hydrogels was highlighted by polarized light microscopy, while scanning electron microscopy showed their microporous morphology. Furthermore, the in vitro fungicidal activity was investigated on two fungal strains and the in vitro release curves of the antifungal aldehyde triggered by the pH stimulus were drawn. The theoretical model was developed starting from the hypothesis that the imine-chitosan system, both structurally and functionally, can be assimilated, from a mathematical point of view, with a multifractal object, and its dynamics were analyzed in the framework of the Scale Relativity Theory. Thus, through Riccati-type gauges, two synchronous dynamics, one in the scale space, associated with the fungicidal activity, and the other in the usual space, associated with the antifungal aldehyde release, become operational. Their synchronicity, reducible to the isomorphism of two SL(2R)-type groups, implies, by means of its joint invariant functions, bioactive aldehyde compound release dynamics in the form of “kink–antikink pairs” dynamics of a multifractal type. Finally, the theoretical model was validated through the experimental data." @default.
- W3148399466 created "2021-04-13" @default.
- W3148399466 creator A5001789544 @default.
- W3148399466 creator A5007953899 @default.
- W3148399466 creator A5010233611 @default.
- W3148399466 creator A5031101512 @default.
- W3148399466 creator A5037440558 @default.
- W3148399466 creator A5043446030 @default.
- W3148399466 creator A5044301622 @default.
- W3148399466 creator A5073521748 @default.
- W3148399466 date "2021-04-06" @default.
- W3148399466 modified "2023-10-18" @default.
- W3148399466 title "A Theoretical Model for Release Dynamics of an Antifungal Agent Covalently Bonded to the Chitosan" @default.
- W3148399466 cites W1977858750 @default.
- W3148399466 cites W2074563691 @default.
- W3148399466 cites W2123542901 @default.
- W3148399466 cites W2142607208 @default.
- W3148399466 cites W2159232912 @default.
- W3148399466 cites W2160554459 @default.
- W3148399466 cites W2174399815 @default.
- W3148399466 cites W2461181046 @default.
- W3148399466 cites W2810936709 @default.
- W3148399466 cites W2890636082 @default.
- W3148399466 cites W2897262713 @default.
- W3148399466 cites W2955729572 @default.
- W3148399466 cites W2956927427 @default.
- W3148399466 cites W2968294063 @default.
- W3148399466 cites W2971020897 @default.
- W3148399466 cites W3027323441 @default.
- W3148399466 cites W3037629347 @default.
- W3148399466 cites W3045730098 @default.
- W3148399466 cites W3046880059 @default.
- W3148399466 cites W3080383785 @default.
- W3148399466 cites W3125126530 @default.
- W3148399466 doi "https://doi.org/10.3390/molecules26072089" @default.
- W3148399466 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8038756" @default.
- W3148399466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33917359" @default.
- W3148399466 hasPublicationYear "2021" @default.
- W3148399466 type Work @default.
- W3148399466 sameAs 3148399466 @default.
- W3148399466 citedByCount "4" @default.
- W3148399466 countsByYear W31483994662021 @default.
- W3148399466 countsByYear W31483994662022 @default.
- W3148399466 crossrefType "journal-article" @default.
- W3148399466 hasAuthorship W3148399466A5001789544 @default.
- W3148399466 hasAuthorship W3148399466A5007953899 @default.
- W3148399466 hasAuthorship W3148399466A5010233611 @default.
- W3148399466 hasAuthorship W3148399466A5031101512 @default.
- W3148399466 hasAuthorship W3148399466A5037440558 @default.
- W3148399466 hasAuthorship W3148399466A5043446030 @default.
- W3148399466 hasAuthorship W3148399466A5044301622 @default.
- W3148399466 hasAuthorship W3148399466A5073521748 @default.
- W3148399466 hasBestOaLocation W31483994661 @default.
- W3148399466 hasConcept C108586683 @default.
- W3148399466 hasConcept C161790260 @default.
- W3148399466 hasConcept C178790620 @default.
- W3148399466 hasConcept C180577832 @default.
- W3148399466 hasConcept C185592680 @default.
- W3148399466 hasConcept C21951064 @default.
- W3148399466 hasConcept C2776573223 @default.
- W3148399466 hasConcept C2779732960 @default.
- W3148399466 hasConcept C2779825165 @default.
- W3148399466 hasConceptScore W3148399466C108586683 @default.
- W3148399466 hasConceptScore W3148399466C161790260 @default.
- W3148399466 hasConceptScore W3148399466C178790620 @default.
- W3148399466 hasConceptScore W3148399466C180577832 @default.
- W3148399466 hasConceptScore W3148399466C185592680 @default.
- W3148399466 hasConceptScore W3148399466C21951064 @default.
- W3148399466 hasConceptScore W3148399466C2776573223 @default.
- W3148399466 hasConceptScore W3148399466C2779732960 @default.
- W3148399466 hasConceptScore W3148399466C2779825165 @default.
- W3148399466 hasIssue "7" @default.
- W3148399466 hasLocation W31483994661 @default.
- W3148399466 hasLocation W31483994662 @default.
- W3148399466 hasOpenAccess W3148399466 @default.
- W3148399466 hasPrimaryLocation W31483994661 @default.
- W3148399466 hasRelatedWork W1966822686 @default.
- W3148399466 hasRelatedWork W2047888616 @default.
- W3148399466 hasRelatedWork W2065117182 @default.
- W3148399466 hasRelatedWork W2328763573 @default.
- W3148399466 hasRelatedWork W2944711987 @default.
- W3148399466 hasRelatedWork W3034247094 @default.
- W3148399466 hasRelatedWork W3088572931 @default.
- W3148399466 hasRelatedWork W3093226356 @default.
- W3148399466 hasRelatedWork W4379966691 @default.
- W3148399466 hasRelatedWork W4379985726 @default.
- W3148399466 hasVolume "26" @default.
- W3148399466 isParatext "false" @default.
- W3148399466 isRetracted "false" @default.
- W3148399466 magId "3148399466" @default.
- W3148399466 workType "article" @default.