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- W3148431034 abstract "The paired box domain gene 5 (PAX5) is frequently altered in both childhood and adult B-cell acute lymphoblastic leukemia, and takes part in leukemogenesis. We analyzed data from the database of Gene Expression Omnibus (accession number: GSE11877) using bioinformatical and statistical methods. The results showed that cases of PAX5 alteration can cluster using unsupervised clustering algorithms, and one gene, zinc and ring finger 1 (ZNRF1), was character- ized and validated by quantitative RT-PCR. ZNRF1 may be associated with leukemogenesis of ALL with PAX5 alteration." @default.
- W3148431034 created "2021-04-13" @default.
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- W3148431034 date "2013-01-01" @default.
- W3148431034 modified "2023-09-26" @default.
- W3148431034 title "PAX5 alteration-associated gene-expression signatures in B-cell acute lymphoblastic leukemia" @default.
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