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- W3148478972 abstract "Midkine (MK ) ，一个肝磷脂绑定生长因素，能调整房间生长，幸存和区别。MK 在许多人的癌在高水平被表示。最近，尿和浆液 MK 集中在胃的癌症病人被分析。然而，有肿瘤和它在肿瘤纸巾的蛋白质表达式的地点的范畴的 clinicopathological 变量的 cytokine mRNA 表达式的协会仍然是逃犯的。MK mRNA 表示从通过手术，健康胃的纸巾(9 个盒子) 的 resected 标本，胃的癌症纸巾和邻近癌症(37 个盒子) 的匹配的非癌的纸巾被反向的 transcriptase 聚合酶链反应(RT-PCR ) 和即时 PCR 估计。Immunohistochemical 分析被执行在胃的癌症定位 MK。在胃的癌症的 MK mRNA 的表示在非癌的纸巾和控制织物样品比那在肿瘤纸巾是高得多的。并且它的表示显著地与 pTNM 阶段和远转移，然而并非与区别等级，肿瘤尺寸和节的参与被联系。MK 蛋白质在肿瘤是无所不在的，特别在肿瘤的 adenoid 部分。另外，它在肿瘤房间的细胞质被发现并且高度在原子核和核专注。在中国病人的胃的肿瘤纸巾的 MK 的表示水平和地点可能与肿瘤开始和前进有关。进一步的学习在在胃的 tumorigenesis 和肿瘤生长的 MK 的机制上是必要的。" @default.
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- W3148478972 date "2007-01-01" @default.
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- W3148478972 title "The Expression and Location of Midkine in Gastric Carcinomas of Chinese Patients" @default.
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