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- W3148486693 abstract "这研究是目的通过我们的实验室以前开发的温和离子的冻结方法为不可溶解的药交货开发新奇 cyclodextrin/chitosan (CD/CS ) nanocarriers。一系列不同 -cyclodextrin (-CD) 衍生物包括 hydroxypropyl 被合并到 CS nanoparticles -- cyclodextrin (HP -- CD ) ， sulphobutylether -- cyclodextrin (SB -- CD ) ，并且 2,6-di-O-methy--cyclodextrin (DM -- CD ) 。为 CD/CS nanoparticles 的物理化学的性质上的 nanoparticle 准备和他们的效果的各种各样的进程参数被调查，例如 CD 衍生物， CD 和 CS 集中，到 TPP (CS/TPP ) 的 CS 的集体比率，和 pH 的类型值。处于最佳的条件， CD/CS nanoparticles 从 30.22mV 在 215276nm 并且与希腊语的第六个字母潜力的尺寸范围被获得到 35.79mV。而且，稳定性学习证明 CD 的加入在 pH 在 PBS 缓冲区使 CD/CS nanocarriers 变为比 CS nanoparticles 更稳定 6.8。为他们在 nanoparticle 形成以及 CD 衍生物的多样化的恐水病的核心的容易的准备和可调节的参数， CD/CS nanoparticles 此处开发了的小说可能与不同物理化学的性质为许多糟糕水溶性的药代表一个有趣、万用的药交货平台。" @default.
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- W3148486693 date "2015-01-01" @default.
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- W3148486693 title "Novel nanoparticles composed of chitosan and β-cyclodextrin derivatives as potential insoluble drug carrier" @default.
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