FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W31485059> ?p ?o ?g. }

• W31485059 endingPage "159" @default.
• W31485059 startingPage "149" @default.
• W31485059 abstract "Many coenzymes are vitamins that are assimilated in mammals into their active form from precursors obtained from the diet. They are often both rare and reactive rendering the likelihood low that the cell uses a collision-based strategy for their delivery to dependent enzymes. In humans, there are only two known B12 or cobalamin-dependent enzymes: methionine synthase and methylmalonyl-CoA mutase. However, the pathway for intracellular assimilation and utilization of this cofactor is complex as revealed by careful clinical analyses of fibroblasts from patients with disorders of cobalamin metabolism. In the recent past, six of the eight human genes involved in the B12 pathway have been identified and these have yielded important insights into their roles. The recent literature on the encoded proteins is reviewed, and a model for intracellular B12 trafficking is proposed in which B12 is escorted to its target proteins in the cytoplasmic and mitochondrial compartments in complex with chaperones, thereby averting problems of dilution and adventitious side reactions." @default.
• W31485059 created "2016-06-24" @default.
• W31485059 creator A5013907641 @default.
• W31485059 date "2006-04-01" @default.
• W31485059 modified "2023-10-16" @default.
• W31485059 title "B₁₂ Trafficking in Mammals: A Case for Coenzyme Escort Service" @default.
• W31485059 cites W1519215275 @default.
• W31485059 cites W1525040400 @default.
• W31485059 cites W1900801421 @default.
• W31485059 cites W1965555344 @default.
• W31485059 cites W1969058620 @default.
• W31485059 cites W1982613368 @default.
• W31485059 cites W1983949602 @default.
• W31485059 cites W1984062414 @default.
• W31485059 cites W1986091806 @default.
• W31485059 cites W1986647498 @default.
• W31485059 cites W1989003913 @default.
• W31485059 cites W1989282758 @default.
• W31485059 cites W1993929117 @default.
• W31485059 cites W1993933577 @default.
• W31485059 cites W2000924367 @default.
• W31485059 cites W2001525363 @default.
• W31485059 cites W2004835079 @default.
• W31485059 cites W2005813681 @default.
• W31485059 cites W2006001399 @default.
• W31485059 cites W2007794598 @default.
• W31485059 cites W2010524227 @default.
• W31485059 cites W2015682589 @default.
• W31485059 cites W2019073992 @default.
• W31485059 cites W2019965458 @default.
• W31485059 cites W2023806522 @default.
• W31485059 cites W2026629228 @default.
• W31485059 cites W2028621474 @default.
• W31485059 cites W2032571964 @default.
• W31485059 cites W2032647645 @default.
• W31485059 cites W2033579455 @default.
• W31485059 cites W2034527294 @default.
• W31485059 cites W2042160325 @default.
• W31485059 cites W2042317540 @default.
• W31485059 cites W2046329665 @default.
• W31485059 cites W2048903985 @default.
• W31485059 cites W2050130395 @default.
• W31485059 cites W2052434481 @default.
• W31485059 cites W2052624193 @default.
• W31485059 cites W2057469776 @default.
• W31485059 cites W2058375092 @default.
• W31485059 cites W2058653907 @default.
• W31485059 cites W2058691613 @default.
• W31485059 cites W2059636894 @default.
• W31485059 cites W2061040884 @default.
• W31485059 cites W2069203589 @default.
• W31485059 cites W2071218376 @default.
• W31485059 cites W2072871401 @default.
• W31485059 cites W2077167882 @default.
• W31485059 cites W2079491588 @default.
• W31485059 cites W2080372186 @default.
• W31485059 cites W2085772402 @default.
• W31485059 cites W2086098893 @default.
• W31485059 cites W2087145426 @default.
• W31485059 cites W2088723535 @default.
• W31485059 cites W2091979836 @default.
• W31485059 cites W2094612201 @default.
• W31485059 cites W2094845742 @default.
• W31485059 cites W2110425964 @default.
• W31485059 cites W2114702800 @default.
• W31485059 cites W2116225082 @default.
• W31485059 cites W2123797674 @default.
• W31485059 cites W2130271075 @default.
• W31485059 cites W2138516874 @default.
• W31485059 cites W2142937845 @default.
• W31485059 cites W2143351258 @default.
• W31485059 cites W2145112140 @default.
• W31485059 cites W2145527558 @default.
• W31485059 cites W2148725983 @default.
• W31485059 cites W2152552555 @default.
• W31485059 cites W2156435321 @default.
• W31485059 cites W2159577160 @default.
• W31485059 cites W2162582565 @default.
• W31485059 cites W2412250133 @default.
• W31485059 cites W399814894 @default.
• W31485059 doi "https://doi.org/10.1021/cb6001174" @default.
• W31485059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17163662" @default.
• W31485059 hasPublicationYear "2006" @default.
• W31485059 type Work @default.
• W31485059 sameAs 31485059 @default.
• W31485059 citedByCount "133" @default.
• W31485059 countsByYear W314850592012 @default.
• W31485059 countsByYear W314850592013 @default.
• W31485059 countsByYear W314850592014 @default.
• W31485059 countsByYear W314850592015 @default.
• W31485059 countsByYear W314850592016 @default.
• W31485059 countsByYear W314850592017 @default.
• W31485059 countsByYear W314850592018 @default.
• W31485059 countsByYear W314850592019 @default.
• W31485059 countsByYear W314850592020 @default.
• W31485059 countsByYear W314850592021 @default.
• W31485059 countsByYear W314850592022 @default.
• W31485059 countsByYear W314850592023 @default.

• next