Matches in SemOpenAlex for { <https://semopenalex.org/work/W3148648511> ?p ?o ?g. }
- W3148648511 abstract "We have studied the molecular specification of precursor cells in expanded neurosphere cultures derived from distinct subregions of the embryonic mouse telencephalon. These regionally derived cultures exhibited differential responses to the mitogens EGF and bFGF, suggesting that the precursors in these cultures were differentially specified as is the case in situ. To examine this further, cultures from each of the telencephalic subregions were expanded in both EGF and bFGF before differentiation. The neurons produced displayed molecular phenotypes similar to those normally derived from each of these regions in vivo.Moreover, analysis of gene expression in the undifferentiated cultures showed that the regionally derived neurospheres express many of the same developmental control genes as their in vivo counterparts. Taken together, the present findings suggest that precursor cells in neurosphere cultures, derived from distinct subregions of the embryonic telencephalon, maintain at least certain aspects of their molecular specification, even after significant expansion in vitro." @default.
- W3148648511 created "2021-04-13" @default.
- W3148648511 creator A5038933678 @default.
- W3148648511 creator A5045988049 @default.
- W3148648511 date "2010-01-01" @default.
- W3148648511 modified "2023-09-27" @default.
- W3148648511 title "Regional Specification of Neurosphere Cultures Derived from Subregions of the Embryonic Telencephalon" @default.
- W3148648511 cites W1487222554 @default.
- W3148648511 cites W1547812429 @default.
- W3148648511 cites W1580707798 @default.
- W3148648511 cites W1595834812 @default.
- W3148648511 cites W1715204582 @default.
- W3148648511 cites W1834737933 @default.
- W3148648511 cites W1838548664 @default.
- W3148648511 cites W1857568828 @default.
- W3148648511 cites W1875709550 @default.
- W3148648511 cites W1941550741 @default.
- W3148648511 cites W1968899084 @default.
- W3148648511 cites W1982087641 @default.
- W3148648511 cites W1983482520 @default.
- W3148648511 cites W1989266013 @default.
- W3148648511 cites W1999696388 @default.
- W3148648511 cites W1999747064 @default.
- W3148648511 cites W2002353171 @default.
- W3148648511 cites W2004580866 @default.
- W3148648511 cites W2007264809 @default.
- W3148648511 cites W2009311165 @default.
- W3148648511 cites W2022600603 @default.
- W3148648511 cites W2022671203 @default.
- W3148648511 cites W2023195093 @default.
- W3148648511 cites W2025625968 @default.
- W3148648511 cites W2030486751 @default.
- W3148648511 cites W2034752755 @default.
- W3148648511 cites W2046107611 @default.
- W3148648511 cites W2064520670 @default.
- W3148648511 cites W2064624464 @default.
- W3148648511 cites W2068918006 @default.
- W3148648511 cites W2075281619 @default.
- W3148648511 cites W2079274555 @default.
- W3148648511 cites W2081235375 @default.
- W3148648511 cites W2081768529 @default.
- W3148648511 cites W2084761937 @default.
- W3148648511 cites W2086682158 @default.
- W3148648511 cites W2097053397 @default.
- W3148648511 cites W2104407210 @default.
- W3148648511 cites W2110313558 @default.
- W3148648511 cites W2122199698 @default.
- W3148648511 cites W2123048941 @default.
- W3148648511 cites W2124109473 @default.
- W3148648511 cites W2124633824 @default.
- W3148648511 cites W2127535417 @default.
- W3148648511 cites W2132549779 @default.
- W3148648511 cites W2132691381 @default.
- W3148648511 cites W2135922421 @default.
- W3148648511 cites W2140536312 @default.
- W3148648511 cites W2150207739 @default.
- W3148648511 cites W2150817988 @default.
- W3148648511 cites W2155553885 @default.
- W3148648511 cites W2159617943 @default.
- W3148648511 cites W2161687343 @default.
- W3148648511 cites W2165130538 @default.
- W3148648511 cites W2165682071 @default.
- W3148648511 cites W2254185323 @default.
- W3148648511 cites W2098179655 @default.
- W3148648511 hasPublicationYear "2010" @default.
- W3148648511 type Work @default.
- W3148648511 sameAs 3148648511 @default.
- W3148648511 citedByCount "2" @default.
- W3148648511 countsByYear W31486485112012 @default.
- W3148648511 crossrefType "journal-article" @default.
- W3148648511 hasAuthorship W3148648511A5038933678 @default.
- W3148648511 hasAuthorship W3148648511A5045988049 @default.
- W3148648511 hasConcept C104317684 @default.
- W3148648511 hasConcept C127716648 @default.
- W3148648511 hasConcept C145103041 @default.
- W3148648511 hasConcept C150194340 @default.
- W3148648511 hasConcept C162746124 @default.
- W3148648511 hasConcept C169760540 @default.
- W3148648511 hasConcept C202751555 @default.
- W3148648511 hasConcept C207001950 @default.
- W3148648511 hasConcept C20875687 @default.
- W3148648511 hasConcept C2780597806 @default.
- W3148648511 hasConcept C529278444 @default.
- W3148648511 hasConcept C533869091 @default.
- W3148648511 hasConcept C54355233 @default.
- W3148648511 hasConcept C81439078 @default.
- W3148648511 hasConcept C86803240 @default.
- W3148648511 hasConcept C95444343 @default.
- W3148648511 hasConceptScore W3148648511C104317684 @default.
- W3148648511 hasConceptScore W3148648511C127716648 @default.
- W3148648511 hasConceptScore W3148648511C145103041 @default.
- W3148648511 hasConceptScore W3148648511C150194340 @default.
- W3148648511 hasConceptScore W3148648511C162746124 @default.
- W3148648511 hasConceptScore W3148648511C169760540 @default.
- W3148648511 hasConceptScore W3148648511C202751555 @default.
- W3148648511 hasConceptScore W3148648511C207001950 @default.
- W3148648511 hasConceptScore W3148648511C20875687 @default.
- W3148648511 hasConceptScore W3148648511C2780597806 @default.
- W3148648511 hasConceptScore W3148648511C529278444 @default.
- W3148648511 hasConceptScore W3148648511C533869091 @default.