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• W3148758329 abstract "article Objective. The aim of this study was to investigate the clinical and pathological characteristics of uterine clear cell carcinoma (UCCC) and the treatment of this disease in relation to patient outcomes. Methods. The clinicopathological data for and the management of all patients with UCCC who presented be- tween 1991 and 2010 at 11 member hospitals of the Taiwanese Gynecologic Oncology Group (TGOG) were ret- rospectively reviewed. Results. There were nosignificantdifferencesin5-year overall survival(OS)rates betweenpatients with pure UCCC (n = 100) and non-pure UCCC (n = 53) at the same surgical stage, with OS rates of 92.6%, and 87.7% for stage I; 83.3% and 83.3% for stage II; 64.0% and 67.8% for stage III; and 16.7% and 0% for stage IV (n = 1), respec- tively.TumorstageandageindependentlyinfluencedtheOSrateofUCCC.ForthepatientswithearlystageUCCC, the adjuvant therapy modality was the only significant prognostic factor for recurrence-free survival. The pa- tients with early stage UCCC who received adjuvant therapy had excellent 5-year recurrence-free survival and OS rates compared to those who received radiotherapy (100% vs. 74%, p = 0.01; 100% vs. 72%, p = 0.03). Conclusions. The 5-year survival ratesof patients with pure UCCCand non-pure UCCC were similar. The prog- nosis for surgical staging of patients with stage I/II UCCC was encouraging. Postoperative adjuvant platinum- based chemotherapy is recommended for patients with early stage UCCC who are at a high risk of recurrence." @default.
• W3148758329 created "2021-04-13" @default.
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• W3148758329 date "2014-01-01" @default.
• W3148758329 modified "2023-09-27" @default.
• W3148758329 title "Prognostic factors and treatment outcomes for patients with surgically staged uterine clear cell carcinoma focusing on the early stage: A Taiwanese Gynecologic Oncology Group study☆" @default.
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• W3148758329 hasPublicationYear "2014" @default.
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