Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149016730> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W3149016730 endingPage "335" @default.
- W3149016730 startingPage "335" @default.
- W3149016730 abstract "P84 and integrin associated protein (IAP) are heterophilic binding partners that are expressed in the central nervous system in addition to a variety of other tissues. Both molecules are known to be involved in cell signaling in nonneural tissues. In the retina, both molecules are expressed prominently in plexiform layers, suggesting a possible association with synapses. Here, we examined the cellular expression and ultrastructural localization of the two molecules in the developing mouse retina. Both appeared to be expressed at one or both sides of synaptic sites, although the expression of IAP in the retina precedes that of P84. Examination of transgenic IAP-null retinae revealed a failure of P84 to become associated with synaptic sites, suggesting the interaction of P84 with IAP was necessary for P84's synaptic localization. These findings suggest that the signaling activities of P84 and IAP are localized to sites of synaptic contact in the retina. Thus this pair of synapse-associated molecules represents a bidirectional signaling system that could function to modify synaptic activity or possibly trophic interactions between central neurons. J. Comp. Neurol. 416:335–344, 2000. © 2000 Wiley-Liss, Inc." @default.
- W3149016730 created "2021-04-13" @default.
- W3149016730 creator A5049963065 @default.
- W3149016730 creator A5050073634 @default.
- W3149016730 creator A5050774583 @default.
- W3149016730 creator A5055181418 @default.
- W3149016730 creator A5063875638 @default.
- W3149016730 creator A5072185536 @default.
- W3149016730 date "2000-01-17" @default.
- W3149016730 modified "2023-09-26" @default.
- W3149016730 title "Expression of a synapse-associated membrane protein, P84/SHPS-1, and its ligand, IAP/CD47, in mouse retina" @default.
- W3149016730 doi "https://doi.org/10.1002/(sici)1096-9861(20000117)416:3<335::aid-cne5>3.3.co;2-o" @default.
- W3149016730 hasPublicationYear "2000" @default.
- W3149016730 type Work @default.
- W3149016730 sameAs 3149016730 @default.
- W3149016730 citedByCount "0" @default.
- W3149016730 crossrefType "journal-article" @default.
- W3149016730 hasAuthorship W3149016730A5049963065 @default.
- W3149016730 hasAuthorship W3149016730A5050073634 @default.
- W3149016730 hasAuthorship W3149016730A5050774583 @default.
- W3149016730 hasAuthorship W3149016730A5055181418 @default.
- W3149016730 hasAuthorship W3149016730A5063875638 @default.
- W3149016730 hasAuthorship W3149016730A5072185536 @default.
- W3149016730 hasConcept C127445978 @default.
- W3149016730 hasConcept C169760540 @default.
- W3149016730 hasConcept C185592680 @default.
- W3149016730 hasConcept C2777093970 @default.
- W3149016730 hasConcept C2777585161 @default.
- W3149016730 hasConcept C86803240 @default.
- W3149016730 hasConcept C95444343 @default.
- W3149016730 hasConceptScore W3149016730C127445978 @default.
- W3149016730 hasConceptScore W3149016730C169760540 @default.
- W3149016730 hasConceptScore W3149016730C185592680 @default.
- W3149016730 hasConceptScore W3149016730C2777093970 @default.
- W3149016730 hasConceptScore W3149016730C2777585161 @default.
- W3149016730 hasConceptScore W3149016730C86803240 @default.
- W3149016730 hasConceptScore W3149016730C95444343 @default.
- W3149016730 hasIssue "3" @default.
- W3149016730 hasLocation W31490167301 @default.
- W3149016730 hasOpenAccess W3149016730 @default.
- W3149016730 hasPrimaryLocation W31490167301 @default.
- W3149016730 hasRelatedWork W1569979254 @default.
- W3149016730 hasRelatedWork W1986302039 @default.
- W3149016730 hasRelatedWork W1999352891 @default.
- W3149016730 hasRelatedWork W2003186848 @default.
- W3149016730 hasRelatedWork W2008868337 @default.
- W3149016730 hasRelatedWork W2012730786 @default.
- W3149016730 hasRelatedWork W2083988726 @default.
- W3149016730 hasRelatedWork W2917021200 @default.
- W3149016730 hasRelatedWork W3190829079 @default.
- W3149016730 hasRelatedWork W4366352776 @default.
- W3149016730 hasVolume "416" @default.
- W3149016730 isParatext "false" @default.
- W3149016730 isRetracted "false" @default.
- W3149016730 magId "3149016730" @default.
- W3149016730 workType "article" @default.