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- W314905215 abstract "The mammalian Y chromosome contains a locus ( Sry ) that is responsible for the developmental switch causing the formation of testes in males. Sry is the mammalian testes determination factor and is found only in placental mammals and marsupials but not monotremes. Sry is a high-mobility group (HMG) box containing transcription factor. The HMG region is highly conserved in mammalian Sry loci, and regions outside of the HMG box are less well conserved. Sry was probably derived from Sox3 , an X-linked locus, in the formation of the modern mammalian X and Y chromosomes from an ancestral chromosome pair containing Sox3. Sry is also expressed in other tissues in adult mammalian males and may have other functions in males." @default.
- W314905215 created "2016-06-24" @default.
- W314905215 creator A5043225771 @default.
- W314905215 date "2013-01-01" @default.
- W314905215 modified "2023-09-24" @default.
- W314905215 title "Testes-Determining Locus" @default.
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- W314905215 doi "https://doi.org/10.1016/b978-0-12-374984-0.01530-8" @default.
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