Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149261769> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3149261769 abstract "Objective To study the expression of lipopolysaccharide(LPS) receptor CD14 and Toll-like receptor 4 (TLR4) on Kupffer cells and its role in ischemia-reperfusion injury (IRI) on rat liver graft. Methods The Kupffer cells following IRI were isolated and divided into control, ischemia-reperfusion (IR), and anti-CD14 antibody group. The mRNA and protein expression of CD14 and TLR4, nuclear factor kappa B (NF-κB) activity and TNF-α level in supernatant were measured. Results The mRNA and protein expression of CD14 and TLR4 in IR group were significantly higher than those in control group~(P0.01). The NF-κB activity and TNF-α level in IR group were significantly higher than those in control group(P0.01), and they greatly decreased after anti CD14 antibody treatment (compared with IR group, P0.05), but were still significantly higher than those in control group(P0.01). Conclusions LPS following IRI could up-regulate CD14 and TLR4 gene and protein expression on Kupffer cells, and subsequently activate NF-κB to produce cytokines, but other signal transduction pathways might also participate in the IRI." @default.
- W3149261769 created "2021-04-13" @default.
- W3149261769 creator A5023536093 @default.
- W3149261769 date "2005-01-01" @default.
- W3149261769 modified "2023-09-23" @default.
- W3149261769 title "Expression of CD14 and Toll-like receptor 4 on Kupffer cells and its role in ischemia-reperfusion injury on rat liver graft" @default.
- W3149261769 hasPublicationYear "2005" @default.
- W3149261769 type Work @default.
- W3149261769 sameAs 3149261769 @default.
- W3149261769 citedByCount "0" @default.
- W3149261769 crossrefType "journal-article" @default.
- W3149261769 hasAuthorship W3149261769A5023536093 @default.
- W3149261769 hasConcept C104317684 @default.
- W3149261769 hasConcept C105580179 @default.
- W3149261769 hasConcept C126322002 @default.
- W3149261769 hasConcept C134018914 @default.
- W3149261769 hasConcept C136449434 @default.
- W3149261769 hasConcept C170493617 @default.
- W3149261769 hasConcept C17991360 @default.
- W3149261769 hasConcept C203014093 @default.
- W3149261769 hasConcept C2776070231 @default.
- W3149261769 hasConcept C2776709828 @default.
- W3149261769 hasConcept C2776914184 @default.
- W3149261769 hasConcept C2778513237 @default.
- W3149261769 hasConcept C2778754761 @default.
- W3149261769 hasConcept C2778904781 @default.
- W3149261769 hasConcept C2780114680 @default.
- W3149261769 hasConcept C541997718 @default.
- W3149261769 hasConcept C55493867 @default.
- W3149261769 hasConcept C62478195 @default.
- W3149261769 hasConcept C71924100 @default.
- W3149261769 hasConcept C86803240 @default.
- W3149261769 hasConcept C95444343 @default.
- W3149261769 hasConceptScore W3149261769C104317684 @default.
- W3149261769 hasConceptScore W3149261769C105580179 @default.
- W3149261769 hasConceptScore W3149261769C126322002 @default.
- W3149261769 hasConceptScore W3149261769C134018914 @default.
- W3149261769 hasConceptScore W3149261769C136449434 @default.
- W3149261769 hasConceptScore W3149261769C170493617 @default.
- W3149261769 hasConceptScore W3149261769C17991360 @default.
- W3149261769 hasConceptScore W3149261769C203014093 @default.
- W3149261769 hasConceptScore W3149261769C2776070231 @default.
- W3149261769 hasConceptScore W3149261769C2776709828 @default.
- W3149261769 hasConceptScore W3149261769C2776914184 @default.
- W3149261769 hasConceptScore W3149261769C2778513237 @default.
- W3149261769 hasConceptScore W3149261769C2778754761 @default.
- W3149261769 hasConceptScore W3149261769C2778904781 @default.
- W3149261769 hasConceptScore W3149261769C2780114680 @default.
- W3149261769 hasConceptScore W3149261769C541997718 @default.
- W3149261769 hasConceptScore W3149261769C55493867 @default.
- W3149261769 hasConceptScore W3149261769C62478195 @default.
- W3149261769 hasConceptScore W3149261769C71924100 @default.
- W3149261769 hasConceptScore W3149261769C86803240 @default.
- W3149261769 hasConceptScore W3149261769C95444343 @default.
- W3149261769 hasLocation W31492617691 @default.
- W3149261769 hasOpenAccess W3149261769 @default.
- W3149261769 hasPrimaryLocation W31492617691 @default.
- W3149261769 hasRelatedWork W1976423738 @default.
- W3149261769 hasRelatedWork W1982006000 @default.
- W3149261769 hasRelatedWork W2046393778 @default.
- W3149261769 hasRelatedWork W2057758077 @default.
- W3149261769 hasRelatedWork W2080552152 @default.
- W3149261769 hasRelatedWork W2089573702 @default.
- W3149261769 hasRelatedWork W2113284615 @default.
- W3149261769 hasRelatedWork W2143461874 @default.
- W3149261769 hasRelatedWork W2153251153 @default.
- W3149261769 hasRelatedWork W2351065648 @default.
- W3149261769 hasRelatedWork W2353916976 @default.
- W3149261769 hasRelatedWork W2364428194 @default.
- W3149261769 hasRelatedWork W2364790939 @default.
- W3149261769 hasRelatedWork W2391565288 @default.
- W3149261769 hasRelatedWork W2405499503 @default.
- W3149261769 hasRelatedWork W2413117882 @default.
- W3149261769 hasRelatedWork W2418087297 @default.
- W3149261769 hasRelatedWork W3031525039 @default.
- W3149261769 hasRelatedWork W3113984120 @default.
- W3149261769 hasRelatedWork W3122447178 @default.
- W3149261769 isParatext "false" @default.
- W3149261769 isRetracted "false" @default.
- W3149261769 magId "3149261769" @default.
- W3149261769 workType "article" @default.