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- W3149295098 abstract "Little is known about the light phenotype of SARS-CoV-2 pneumonia, which behaves in an unusual way, unlike other known respiratory diseases. We believe that the histopathological features of early COVID-19 could be considered the pathophysiological hallmark of this disease. Lung cryobiopsies show almost pristine alveoli, enlarged/hyperplasic alveolar capillaries along with dilatation of the post capillary pulmonary venules. Hypoxemia could therefore be explained by a reduction of the normal V/Q ratio, due to blood overflow around well ventilated alveoli. This could clarify typical manifestations of type L COVID-19, such as happy hypoxemia, response to awake prone positioning, response to PEEP/CPAP and platypnea orthodeoxia." @default.
- W3149295098 created "2021-04-13" @default.
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- W3149295098 date "2022-09-01" @default.
- W3149295098 modified "2023-09-26" @default.
- W3149295098 title "Pathophysiology of light phenotype SARS-CoV-2 interstitial pneumonia: from histopathological features to clinical presentations" @default.
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- W3149295098 doi "https://doi.org/10.1016/j.pulmoe.2021.03.003" @default.
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