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- W3149353735 abstract "瞄准：评估醇脱氢酶 2 的影响(ADH2 ) 和醛脱氢酶 2 (ALDH2 ) 食道的癌症上的多型性冒的风险。方法：从 Yanting 县的 191 个食道的癌症病人和 198 健康控制在这研究被注册。ADH2 和 ALDH2 遗传型被 polymerase-chain-reaction 与 confronting-two-pair-primer (PCR-CTPP ) 检验方法。无条件的逻辑回归被用来计算机会比率(或) 并且 95% 信心间隔(95% CI ) 。结果：两 ADH2 *1 等位基因和 ALDH2 *1 /*2 等位基因显示出得食道的癌症的增加的风险。调整或(95% CI ) 为 ADH2 *1 等位基因，与 ADH2 *2 / 相比， *2 是 1.65 (95% CI = 1.02-2.68 ) 并且 1.67 (95% CI = 1.02-2.72 ) 为 ALDH2 *1 /*2 与 ALDH2 相比 *1 /*1。在 ALDH2 之间的一个重要相互作用并且喝关于食道的癌症风险被检测， OR 是 1.83 (95% CI = 1.13-2.95 ) 。而且，什么时候与 ADH2 *2 / *2 和 ALDH2 *1 / *1 搬运人，相比， ADH2 *1 和 ALDH2 *2 搬运人显示出在非白酒喝酒者之中得食道的癌症的提高的风险(或= 2.46 ，95% CI = 0.98-6.14 )，并且在白酒喝酒者之中在白酒喝酒者之中得食道的癌症的显著地提高的风险(或= 9.86 ，95% CI = 3.10-31.38 )。结论：ADH2 和 ALDH2 遗传型与食道的癌症风险被联系。ADH2 *1 等位基因和 ALDH2 *2 等位基因搬运人有得食道的癌症的高得多的风险，特别在白酒喝酒者之中。" @default.
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- W3149353735 date "2007-01-01" @default.
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- W3149353735 title "Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China" @default.
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