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- W3149389910 abstract "To determine the value of dual-energy CT (DECT) and combined information of perfusion and angiography in diagnosing coronary artery disease (CAD), with single photon emission computed tomography (SPECT) and quantitative coronary angiography (QCA) as a reference standard. Thirty- four patients were enrolled in this study. DECT was used as a contrast-enhanced retrospectively ECG- gated scan protocol during the rest state and tubes were set at 140/100 kV. DECT angiography (DE- CTA) and DECT perfusion (DE-CTP) were calcu- lated from two kV images. DE-CTP results were compared with SPECT and DE-CTA with QCA, respectively. The combined DE-CTP with DE-CTA data were compared to QCA in diagnosis of obstruc- tive CAD (stenosis C 50%). DECT showed diagnos- tic image quality in 31 patients. Using SPECT as a reference, DE-CTP had sensitivity of 68%, specificity of 93%, and sensitivity of 81%, and specificity of 92% for identifying any type of perfusion deficits on the segment- and territory-based analysis, respec- tively. Using QCA as a reference standard, DE-CTA showed sensitivity of 82%, specificity of 91% and accuracy of 86% for detecting C50% coronary stenosis on the vessel-based analysis, whereas the combination of DE-CTA and DE-CTP gave sensitiv- ity of 90%, specificity of 86% and accuracy of 88% for detecting C50% coronary stenosis, respectively. Combination of DE-CTP and DE-CTA may improve diagnostic performance compared to CTA alone for the diagnosis of significant coronary stenosis." @default.
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- W3149389910 date "2011-01-01" @default.
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- W3149389910 title "Incremental value of dual-energy CT to coronary CT angiography for the detection of significant coronary stenosis: comparison with quantitative coronary angiography and single photon emission computed" @default.
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