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- W3149443755 abstract "心血管的老化是逐渐地导致结构的退化和所有心脏、脉管的部件的功能的损失的一个生理的过程。传导系统被变老的过程深深地也在临床的方面与相关反射影响。年龄相关的心律不齐带重要病态和死亡并且代表临床、节俭的负担。在老化的 pathophysiology 的一位重要、不义地未被认出的演员被细胞外的矩阵(ECM ) 代表那在结构上不仅支持决定它的机械、功能的性质的心，而且送一个生物发信号调整细胞的功能并且维持织物动态平衡。在生物物理的水平，心脏的 ECM 展出 anisotropy 的古怪的度，它在专业化电的传导系统的传导性的性质的主要决定因素之中。心脏的 ECM 的联系年龄的改变因此能深刻地在耐心的临床的条件上与惹人注目的影响影响传导系统的函数。这评论将集中于在心传导系统并且在他们的翻译以后发生在老化期间到临床的情形的 ECM 变化。诊断的潜力并且 therapeutical 观点在 ECM 联系年龄的改变上从知识产生进一步被讨论。" @default.
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- W3149443755 date "2015-01-01" @default.
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- W3149443755 title "The role of extracellular matrix in age-related conduction disorders： a forgotten player？" @default.
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