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- W3149449583 endingPage "180" @default.
- W3149449583 startingPage "167" @default.
- W3149449583 abstract "Aquaporins (AQP) are a class of water channel membrane proteins that are widely expressed in the gut. The biological functions of aquaporins, which regulate the absorption and secretion of water molecules and small solutes, maintain the stable state of the intestine, regulate cell proliferation and migration, participate in the process of intestinal inflammation, and mediate tumorigenesis, demonstrate the physiological significance of these channels in intestinal health. The pathology of many intestinal diseases is associated with changes in the location and expression of aquaporins, such as intestinal infection, which can change the expression and distribution of AQPs in intestinal tissues/cells by affecting cytokines and chemokines. This can lead to various intestinal diseases such as diarrhoea, which also suggests the importance of aquaporins in the prevention and treatment of intestinal diseases. This review summarizes the relationship between aquaporins and intestinal physiology and diseases and focuses on drugs (such as plant extracts) or diets that can regulate intestinal health by regulating aquaporins. It provides a basis for establishing aquaporins as biomarkers and therapeutic targets for intestinal health." @default.
- W3149449583 created "2021-04-13" @default.
- W3149449583 creator A5010144767 @default.
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- W3149449583 creator A5050550868 @default.
- W3149449583 creator A5060002817 @default.
- W3149449583 creator A5063399698 @default.
- W3149449583 creator A5073001021 @default.
- W3149449583 date "2021-04-03" @default.
- W3149449583 modified "2023-10-14" @default.
- W3149449583 title "Aquaporin: targets for dietary nutrients to regulate intestinal health" @default.
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