Matches in SemOpenAlex for { <https://semopenalex.org/work/W31496> ?p ?o ?g. }
- W31496 endingPage "261" @default.
- W31496 startingPage "249" @default.
- W31496 abstract "The familial occurrence of alcoholism has been known for many years. Many twin, adoption, and family studies now concur that this familial pattern is to a great extent conferred by genes transmitted to biological offspring (1,2). Approximately 50–60% of individual differences in risk for alcoholism is genetic, and this proportion is approximately equal in men and women (2). Thus, it is an easy task to predict that a close biological relative of an alcoholic is at higher risk for alcoholism. However, risk is not inherited alleles at specific risk-promoting or -protective genes are inherited. To date, there are only two specific genes known to confer substantial protection against alcoholism, variants at the ALDH2*2 and ADH2*2 metabolic enzymes. The variant alleles lead to the accumulation of alcohol’ s metabolite, acetaldehyde, when susceptible individuals drink alcohol. This toxic compound produces nausea, flushing, dizziness, and other unpleasant effects, and slow alcohol metabolizers avoid excessive drinking (3). Therefore, progress from assigning risk statistically to ascertaining whether specific individuals possess risk-promoting or -protective alleles will require the identification of the specific genes underlying risk." @default.
- W31496 created "2016-06-24" @default.
- W31496 creator A5038492593 @default.
- W31496 date "2003-01-01" @default.
- W31496 modified "2023-09-23" @default.
- W31496 title "Current Strategies for Identifying Genes for Alcohol Sensitivity" @default.
- W31496 cites W1484962195 @default.
- W31496 cites W1486648147 @default.
- W31496 cites W1486985822 @default.
- W31496 cites W1495277562 @default.
- W31496 cites W1516178287 @default.
- W31496 cites W1520475080 @default.
- W31496 cites W1521710408 @default.
- W31496 cites W1692860826 @default.
- W31496 cites W1734153454 @default.
- W31496 cites W1816932740 @default.
- W31496 cites W1937687163 @default.
- W31496 cites W1962813951 @default.
- W31496 cites W1964524363 @default.
- W31496 cites W1966581620 @default.
- W31496 cites W1970336334 @default.
- W31496 cites W1974677919 @default.
- W31496 cites W1976741643 @default.
- W31496 cites W1984744289 @default.
- W31496 cites W1986991051 @default.
- W31496 cites W1995636218 @default.
- W31496 cites W1998306498 @default.
- W31496 cites W2002049714 @default.
- W31496 cites W2007771157 @default.
- W31496 cites W2009194067 @default.
- W31496 cites W2010945696 @default.
- W31496 cites W2010972472 @default.
- W31496 cites W2020713314 @default.
- W31496 cites W2028671182 @default.
- W31496 cites W2029360507 @default.
- W31496 cites W2029707852 @default.
- W31496 cites W2031079587 @default.
- W31496 cites W2035268654 @default.
- W31496 cites W2035615794 @default.
- W31496 cites W2038980921 @default.
- W31496 cites W2045679150 @default.
- W31496 cites W2045785057 @default.
- W31496 cites W2047120243 @default.
- W31496 cites W2063618253 @default.
- W31496 cites W2064091856 @default.
- W31496 cites W2069129547 @default.
- W31496 cites W2070035008 @default.
- W31496 cites W2071065596 @default.
- W31496 cites W2072176522 @default.
- W31496 cites W2072748380 @default.
- W31496 cites W2074676512 @default.
- W31496 cites W2081081016 @default.
- W31496 cites W2081336349 @default.
- W31496 cites W2081733449 @default.
- W31496 cites W2083345304 @default.
- W31496 cites W2085229561 @default.
- W31496 cites W2089075373 @default.
- W31496 cites W2095894512 @default.
- W31496 cites W2102763367 @default.
- W31496 cites W2105952206 @default.
- W31496 cites W2112362866 @default.
- W31496 cites W2114836471 @default.
- W31496 cites W2116251096 @default.
- W31496 cites W2117227658 @default.
- W31496 cites W2129772563 @default.
- W31496 cites W2140853028 @default.
- W31496 cites W2143436974 @default.
- W31496 cites W2145081020 @default.
- W31496 cites W2152278608 @default.
- W31496 cites W2156246479 @default.
- W31496 cites W2156578605 @default.
- W31496 cites W2157148415 @default.
- W31496 cites W2160598573 @default.
- W31496 cites W2162674639 @default.
- W31496 cites W2163285329 @default.
- W31496 cites W2315535280 @default.
- W31496 cites W2332405878 @default.
- W31496 cites W2476982389 @default.
- W31496 cites W2485996836 @default.
- W31496 cites W2488968848 @default.
- W31496 cites W3146601713 @default.
- W31496 cites W357886089 @default.
- W31496 cites W612245780 @default.
- W31496 cites W626894320 @default.
- W31496 cites W2037208103 @default.
- W31496 doi "https://doi.org/10.1007/978-1-59259-343-9_13" @default.
- W31496 hasPublicationYear "2003" @default.
- W31496 type Work @default.
- W31496 sameAs 31496 @default.
- W31496 citedByCount "0" @default.
- W31496 crossrefType "journal-article" @default.
- W31496 hasAuthorship W31496A5038492593 @default.
- W31496 hasConcept C104317684 @default.
- W31496 hasConcept C112672928 @default.
- W31496 hasConcept C180754005 @default.
- W31496 hasConcept C2777595113 @default.
- W31496 hasConcept C2779234561 @default.
- W31496 hasConcept C2780161600 @default.