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- W3149606102 abstract "Definition: Localized fibrous tumors of the pleura (LFT) are circumscribed, solid, fibrous and benign lesions of the pleura presenting with scattered spindle-shaped cells of low proliferation rate and low nuclear variance. Their correct diagnosis requires thorough analysis with light microscopy and immunohistochemistry. Imaging techniques, macroscopic or cytological criteria, cannot exclude other diseases, especially malignant variants. The latter are characterized by areas of necrosis, densely packed cells, and higher mitotic index (proliferation rate >5%). Incidence and Etiology: LFT was first described by Lieutaud in 1767 and then by Wagner in 1870. The authors suggested that these lesions might derive from the endothelial layer of the sub-pleural lymphatic vessels. Therefore, the tumors were previously termed “localized fibrous mesothelioma”. LFTs are now classified as separate from malignant pleural mesothelioma. Whether LFTs are true neoplasms or A Publication of the International Pleural Network" @default.
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- W3149606102 date "2016-01-01" @default.
- W3149606102 modified "2023-09-26" @default.
- W3149606102 title "Localized Fibrous Tumor of Pleura" @default.
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- W3149606102 doi "https://doi.org/10.1016/b978-0-323-37706-5.50118-9" @default.
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