Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149644295> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W3149644295 abstract "Rapid occlusion of artificial microvascular grafts (AMGs; less than or equal to 2-mm diameter) by platelet-rich thrombi prevents the clinical use of AMGs in cardiac, vascular, and plastic surgery. Since present antiplatelet agents are unable to assure AMG patency, we have studied the role of specific platelet membrane-glycoprotein blockade on platelet retention by AMGs. In a customized in vitro perfusion chamber, retention on polytetrafluoroethylene (PTFE) AMGs (1.0-mm i.d.) of indium-111-labeled platelets in human whole blood was measured in the presence and absence of inhibitors. Specific blockade of platelet membrane glycoprotein (Gp) IIb/IIIa was achieved using monoclonal antibody 10E5 (10 micrograms/ml) and the peptide GRGDS (Gly-Arg-Gly-Asp-Ser, 0.75 mM). These inhibited 98% and 35%, respectively, of platelet retention under circumstances in which aspirin (7 mM) and dextran (4 mg/ml) inhibited 19% and 18%, respectively, of platelet retention. Nonspecific immunoglobulin G F(ab')2 (10 micrograms/ml) a..." @default.
- W3149644295 created "2021-04-13" @default.
- W3149644295 creator A5000425477 @default.
- W3149644295 creator A5032690949 @default.
- W3149644295 creator A5039026389 @default.
- W3149644295 creator A5056137817 @default.
- W3149644295 creator A5079421632 @default.
- W3149644295 creator A5082611697 @default.
- W3149644295 date "1991-01-01" @default.
- W3149644295 modified "2023-09-23" @default.
- W3149644295 title "Inhibition of platelet retention on artificial microvascular grafts with monoclonal antibodies and a high-affinity peptide directed against platelet membrane glycoproteins." @default.
- W3149644295 hasPublicationYear "1991" @default.
- W3149644295 type Work @default.
- W3149644295 sameAs 3149644295 @default.
- W3149644295 citedByCount "0" @default.
- W3149644295 crossrefType "journal-article" @default.
- W3149644295 hasAuthorship W3149644295A5000425477 @default.
- W3149644295 hasAuthorship W3149644295A5032690949 @default.
- W3149644295 hasAuthorship W3149644295A5039026389 @default.
- W3149644295 hasAuthorship W3149644295A5056137817 @default.
- W3149644295 hasAuthorship W3149644295A5079421632 @default.
- W3149644295 hasAuthorship W3149644295A5082611697 @default.
- W3149644295 hasConcept C108625454 @default.
- W3149644295 hasConcept C126322002 @default.
- W3149644295 hasConcept C146957229 @default.
- W3149644295 hasConcept C153911025 @default.
- W3149644295 hasConcept C159654299 @default.
- W3149644295 hasConcept C185592680 @default.
- W3149644295 hasConcept C203014093 @default.
- W3149644295 hasConcept C26828662 @default.
- W3149644295 hasConcept C2779281246 @default.
- W3149644295 hasConcept C2780009322 @default.
- W3149644295 hasConcept C2993802102 @default.
- W3149644295 hasConcept C542903549 @default.
- W3149644295 hasConcept C55493867 @default.
- W3149644295 hasConcept C71924100 @default.
- W3149644295 hasConcept C86803240 @default.
- W3149644295 hasConcept C89560881 @default.
- W3149644295 hasConcept C98274493 @default.
- W3149644295 hasConceptScore W3149644295C108625454 @default.
- W3149644295 hasConceptScore W3149644295C126322002 @default.
- W3149644295 hasConceptScore W3149644295C146957229 @default.
- W3149644295 hasConceptScore W3149644295C153911025 @default.
- W3149644295 hasConceptScore W3149644295C159654299 @default.
- W3149644295 hasConceptScore W3149644295C185592680 @default.
- W3149644295 hasConceptScore W3149644295C203014093 @default.
- W3149644295 hasConceptScore W3149644295C26828662 @default.
- W3149644295 hasConceptScore W3149644295C2779281246 @default.
- W3149644295 hasConceptScore W3149644295C2780009322 @default.
- W3149644295 hasConceptScore W3149644295C2993802102 @default.
- W3149644295 hasConceptScore W3149644295C542903549 @default.
- W3149644295 hasConceptScore W3149644295C55493867 @default.
- W3149644295 hasConceptScore W3149644295C71924100 @default.
- W3149644295 hasConceptScore W3149644295C86803240 @default.
- W3149644295 hasConceptScore W3149644295C89560881 @default.
- W3149644295 hasConceptScore W3149644295C98274493 @default.
- W3149644295 hasLocation W31496442951 @default.
- W3149644295 hasOpenAccess W3149644295 @default.
- W3149644295 hasPrimaryLocation W31496442951 @default.
- W3149644295 hasRelatedWork W1971583570 @default.
- W3149644295 hasRelatedWork W1982011321 @default.
- W3149644295 hasRelatedWork W2014338575 @default.
- W3149644295 hasRelatedWork W2024096897 @default.
- W3149644295 hasRelatedWork W2041118362 @default.
- W3149644295 hasRelatedWork W2064376293 @default.
- W3149644295 hasRelatedWork W2068283959 @default.
- W3149644295 hasRelatedWork W2076129545 @default.
- W3149644295 hasRelatedWork W2088017612 @default.
- W3149644295 hasRelatedWork W2091785640 @default.
- W3149644295 hasRelatedWork W2107846238 @default.
- W3149644295 hasRelatedWork W2156075488 @default.
- W3149644295 hasRelatedWork W217496567 @default.
- W3149644295 hasRelatedWork W2332983097 @default.
- W3149644295 hasRelatedWork W2363891316 @default.
- W3149644295 hasRelatedWork W2415389038 @default.
- W3149644295 hasRelatedWork W2560846998 @default.
- W3149644295 hasRelatedWork W2921020734 @default.
- W3149644295 hasRelatedWork W61691205 @default.
- W3149644295 hasRelatedWork W85234953 @default.
- W3149644295 isParatext "false" @default.
- W3149644295 isRetracted "false" @default.
- W3149644295 magId "3149644295" @default.
- W3149644295 workType "article" @default.