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- W3149654927 abstract "The aim of this study was to evaluate the clinical efficacy of deep brain stimulation (DBS) and subthalamic nuclei stimulation (STN) in the treatment of Parkinson's disease. A total of 32 patients with Parkinson's disease who continuously treated in our hospital with STN-DBS from November 2011 to November 2013 were selected. All the patients received follow-up evaluation, psychological status questionnaire survey and analysis before surgery and 3 months after surgery using unified Parkinson's disease rating scale (UPDRS), Self-rating depression scale (SDS), and symptom checklist (SCL-90). After turned on the impulse generator (IPG), the daily activities and motor function of UPDRS in all the 32 cases of Parkinson's disease patients were in ''turn off'' state; the mean improvement rates were 51.7 and 60.9 %; when the daily activities and motor function in the state of ''turn on'', the mean improvement rates were 21.4 and 22.3 %. In 20 cases, the preoperative SDS ( 50, the levels of depression, anxiety, somatization, interpersonal sensitivity, hostility, fear, and paranoia of SCL-90 were significant higher than the Chinese traditional levels (P 0.05). Comparison of the preoperative and postoperative depression, somatiza- tion, fear, anxiety, and psychotic factor of SCL-90 found that there was negative correlation between preoperation and postoperation, and the differences were significant (P 0.05), while there were no significant differences in interpersonal sensitivity and paranoia (P ( 0.05). STN- DBS can improve the motor function and ability of daily life of Parkinson's disease patients and can significantly improve the psychological condition of the patients with Parkinson's disease and depression; it is a safe and effec- tive method to the treatment of Parkinson's disease." @default.
- W3149654927 created "2021-04-13" @default.
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- W3149654927 date "2015-01-01" @default.
- W3149654927 modified "2023-09-27" @default.
- W3149654927 title "Effect of Subthalamic Nuclei Electrical Stimulation in the Treatment of Parkinson's Disease" @default.
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