Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149659320> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W3149659320 abstract "[Objective]To investgate the expression of vascular endothelial growth factor in osteonecrosis of the femoral head during the repairing with biodegradable strontium-doped calcium polyphosphate in glucocorticoid-induced rabbits.[Method]Twenty mg/kg methylprednisolone was injected into right gluteus medius muscle at intervals of 24 hours for three times in 21 adult male Japanese white rabbits.Three rabbits were killed randomly at 2 weeks after methylpednisolone injection,both the femora and humeri were histologically examined for the presence of osteonecrosis. The remaining 18 animals with a total of 36 cylindrical 2.5×5 mm femoral head defects were created following the trapdoor procedure. Eighteen animals with femoral head bone defects were randomly divided into three groups. Group A:the defects filled with strontium-doped calcium polyphosphat,Group B:the defects filled with calcium polyphosphate and Group C:the defects filled with autologous cancellous bone alone. Roentgenographic and histological examinations were performed postoperatively. Finally,immunohistochemical analysis using monoclonal antibodies anti-VEGF was performed.[Result]No hip joint dislocation occurred. In Group A,the results of VEGF expression had a significantly difference from those in the other groups 12 weeks after operation. Most of the biodegradable strontium-doped calcium polyphosphate was resorbed and was largely replaced by newly formed trabecular bone at 12 weeks. While in Group B,a major part of defect were repaired. New formed trabecular bone in the defect was very thin. In Group C,morsellized cancellous bone was completely surrounded by fibrous and newly formed trabecular bone. [Conclusion]VEGF expression in the defect of osteonecrosis of the femoral head during the repairing with biodegradable strontium-doped calcium polyphosphate may play a role in stimulating vascular invasion and granulation tissue formation.This may be an important step toward facilitating the resorption in the osteonecrosis,thus impooring the repairing proceduce of femoral head defect." @default.
- W3149659320 created "2021-04-13" @default.
- W3149659320 creator A5000431236 @default.
- W3149659320 date "2010-01-01" @default.
- W3149659320 modified "2023-09-24" @default.
- W3149659320 title "Expression of vascular endothelial growth factor in osteonecrosis of the femoral head during the repairing with biodegradable strontium-doped calcium polyphosphate" @default.
- W3149659320 hasPublicationYear "2010" @default.
- W3149659320 type Work @default.
- W3149659320 sameAs 3149659320 @default.
- W3149659320 citedByCount "0" @default.
- W3149659320 crossrefType "journal-article" @default.
- W3149659320 hasAuthorship W3149659320A5000431236 @default.
- W3149659320 hasConcept C105702510 @default.
- W3149659320 hasConcept C126322002 @default.
- W3149659320 hasConcept C141071460 @default.
- W3149659320 hasConcept C178790620 @default.
- W3149659320 hasConcept C185592680 @default.
- W3149659320 hasConcept C2776350087 @default.
- W3149659320 hasConcept C2777132085 @default.
- W3149659320 hasConcept C2778038992 @default.
- W3149659320 hasConcept C2779100257 @default.
- W3149659320 hasConcept C2780554211 @default.
- W3149659320 hasConcept C519063684 @default.
- W3149659320 hasConcept C71924100 @default.
- W3149659320 hasConceptScore W3149659320C105702510 @default.
- W3149659320 hasConceptScore W3149659320C126322002 @default.
- W3149659320 hasConceptScore W3149659320C141071460 @default.
- W3149659320 hasConceptScore W3149659320C178790620 @default.
- W3149659320 hasConceptScore W3149659320C185592680 @default.
- W3149659320 hasConceptScore W3149659320C2776350087 @default.
- W3149659320 hasConceptScore W3149659320C2777132085 @default.
- W3149659320 hasConceptScore W3149659320C2778038992 @default.
- W3149659320 hasConceptScore W3149659320C2779100257 @default.
- W3149659320 hasConceptScore W3149659320C2780554211 @default.
- W3149659320 hasConceptScore W3149659320C519063684 @default.
- W3149659320 hasConceptScore W3149659320C71924100 @default.
- W3149659320 hasLocation W31496593201 @default.
- W3149659320 hasOpenAccess W3149659320 @default.
- W3149659320 hasPrimaryLocation W31496593201 @default.
- W3149659320 hasRelatedWork W1569967577 @default.
- W3149659320 hasRelatedWork W2041571480 @default.
- W3149659320 hasRelatedWork W2052740991 @default.
- W3149659320 hasRelatedWork W2070923977 @default.
- W3149659320 hasRelatedWork W2351221002 @default.
- W3149659320 hasRelatedWork W2357156822 @default.
- W3149659320 hasRelatedWork W2360031660 @default.
- W3149659320 hasRelatedWork W2378213618 @default.
- W3149659320 hasRelatedWork W2381784534 @default.
- W3149659320 hasRelatedWork W2385832204 @default.
- W3149659320 hasRelatedWork W2389197829 @default.
- W3149659320 hasRelatedWork W2389973700 @default.
- W3149659320 hasRelatedWork W2390749626 @default.
- W3149659320 hasRelatedWork W2393243253 @default.
- W3149659320 hasRelatedWork W2413384706 @default.
- W3149659320 hasRelatedWork W2472398570 @default.
- W3149659320 hasRelatedWork W2979016756 @default.
- W3149659320 hasRelatedWork W3030475347 @default.
- W3149659320 hasRelatedWork W3030698777 @default.
- W3149659320 hasRelatedWork W2292450239 @default.
- W3149659320 isParatext "false" @default.
- W3149659320 isRetracted "false" @default.
- W3149659320 magId "3149659320" @default.
- W3149659320 workType "article" @default.