Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149661016> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3149661016 abstract "SUMMARY Background: A novel 1-h topical method eradicated Helicobacter pylori in 96% of dyspeptic patients. The eradication rate of amoxycillin/omeprazole therapy varies from 0 to 93%. Aim: To compare both methods in patients with endoscopically proven duodenal ulcer. Methods: Eighty patients (59 males, 21 females; median age 43 years) were randomized into two therapeutic groups. The first group (group A) was treated with a 6-week course of ranitidine 300 mg/day, then omeprazole 20 mg b.d. with pronase 36 000 units/day for 2 days, followed by 1-h topical therapy with a solution of bismuth, metronidazole, amoxycillin and pronase. The second group (group B) consisted of patients treated with omeprazole 20 mg b.d. and amoxycillin 2 g/day for 2 weeks, followed by a 4-week course of ranitidine 300 mg/day. Eradication of H. pylori was assessed by urease test, histology, a polymerase chain reaction and a 13 C-urea breath test, all of which were performed 4 weeks after discontinuation of the antibacterial treatment. Results: Eradication rates in groups A and B were 2.5% and 35% in an intention-to-treat analysis, respectively. Side-effects were encountered in 40.5% and 12.5% of subjects in groups A and B, respectively. Treatment tolerance was rated as poor by 54% of patients in group A and 2.5% of patients in group B. Conclusions: Both treatment regimens, the 1-h topical method and amoxycillin with omeprazole, have low eradication rates in patients with duodenal ulcer. In addition, the topical treatment is characterized by a high rate of side-effects and poor tolerance. Based on the results of our study, neither method can be recommended for eradication of H. pylori in patients with duodenal ulcer." @default.
- W3149661016 created "2021-04-13" @default.
- W3149661016 creator A5013368690 @default.
- W3149661016 creator A5019997654 @default.
- W3149661016 date "1998-01-01" @default.
- W3149661016 modified "2023-09-27" @default.
- W3149661016 title "Randomized comparison of 1-hour topical method vs. amoxycillin plus omeprazole for eradication of Helicobacter pylori in duodenal ulcer patients" @default.
- W3149661016 cites W113896798 @default.
- W3149661016 cites W1823239284 @default.
- W3149661016 cites W1862122604 @default.
- W3149661016 cites W1919575822 @default.
- W3149661016 cites W1964480813 @default.
- W3149661016 cites W1966263307 @default.
- W3149661016 cites W2002277566 @default.
- W3149661016 cites W2012038965 @default.
- W3149661016 cites W2038426029 @default.
- W3149661016 cites W2060247990 @default.
- W3149661016 cites W2069631638 @default.
- W3149661016 cites W2098074785 @default.
- W3149661016 cites W2098364251 @default.
- W3149661016 cites W2120816099 @default.
- W3149661016 cites W2320937221 @default.
- W3149661016 cites W2409002706 @default.
- W3149661016 cites W2413051697 @default.
- W3149661016 cites W2418719360 @default.
- W3149661016 cites W2471167462 @default.
- W3149661016 hasPublicationYear "1998" @default.
- W3149661016 type Work @default.
- W3149661016 sameAs 3149661016 @default.
- W3149661016 citedByCount "0" @default.
- W3149661016 crossrefType "journal-article" @default.
- W3149661016 hasAuthorship W3149661016A5013368690 @default.
- W3149661016 hasAuthorship W3149661016A5019997654 @default.
- W3149661016 hasConcept C126322002 @default.
- W3149661016 hasConcept C168563851 @default.
- W3149661016 hasConcept C2775981797 @default.
- W3149661016 hasConcept C2776409635 @default.
- W3149661016 hasConcept C2777396551 @default.
- W3149661016 hasConcept C2777445857 @default.
- W3149661016 hasConcept C2777498785 @default.
- W3149661016 hasConcept C2777785397 @default.
- W3149661016 hasConcept C2778677798 @default.
- W3149661016 hasConcept C2778715236 @default.
- W3149661016 hasConcept C2779708577 @default.
- W3149661016 hasConcept C2780708398 @default.
- W3149661016 hasConcept C3019249092 @default.
- W3149661016 hasConcept C501593827 @default.
- W3149661016 hasConcept C71924100 @default.
- W3149661016 hasConcept C86803240 @default.
- W3149661016 hasConcept C89423630 @default.
- W3149661016 hasConcept C90924648 @default.
- W3149661016 hasConceptScore W3149661016C126322002 @default.
- W3149661016 hasConceptScore W3149661016C168563851 @default.
- W3149661016 hasConceptScore W3149661016C2775981797 @default.
- W3149661016 hasConceptScore W3149661016C2776409635 @default.
- W3149661016 hasConceptScore W3149661016C2777396551 @default.
- W3149661016 hasConceptScore W3149661016C2777445857 @default.
- W3149661016 hasConceptScore W3149661016C2777498785 @default.
- W3149661016 hasConceptScore W3149661016C2777785397 @default.
- W3149661016 hasConceptScore W3149661016C2778677798 @default.
- W3149661016 hasConceptScore W3149661016C2778715236 @default.
- W3149661016 hasConceptScore W3149661016C2779708577 @default.
- W3149661016 hasConceptScore W3149661016C2780708398 @default.
- W3149661016 hasConceptScore W3149661016C3019249092 @default.
- W3149661016 hasConceptScore W3149661016C501593827 @default.
- W3149661016 hasConceptScore W3149661016C71924100 @default.
- W3149661016 hasConceptScore W3149661016C86803240 @default.
- W3149661016 hasConceptScore W3149661016C89423630 @default.
- W3149661016 hasConceptScore W3149661016C90924648 @default.
- W3149661016 hasLocation W31496610161 @default.
- W3149661016 hasOpenAccess W3149661016 @default.
- W3149661016 hasPrimaryLocation W31496610161 @default.
- W3149661016 hasRelatedWork W1016986967 @default.
- W3149661016 hasRelatedWork W16975054 @default.
- W3149661016 hasRelatedWork W2036862598 @default.
- W3149661016 hasRelatedWork W205508698 @default.
- W3149661016 hasRelatedWork W2072510556 @default.
- W3149661016 hasRelatedWork W2084894012 @default.
- W3149661016 hasRelatedWork W2349922941 @default.
- W3149661016 hasRelatedWork W2385370156 @default.
- W3149661016 hasRelatedWork W2387679914 @default.
- W3149661016 hasRelatedWork W2391322570 @default.
- W3149661016 hasRelatedWork W2397767360 @default.
- W3149661016 hasRelatedWork W2405149186 @default.
- W3149661016 hasRelatedWork W2408559488 @default.
- W3149661016 hasRelatedWork W2415461970 @default.
- W3149661016 hasRelatedWork W2418119629 @default.
- W3149661016 hasRelatedWork W2468243937 @default.
- W3149661016 hasRelatedWork W2157669374 @default.
- W3149661016 hasRelatedWork W2572383369 @default.
- W3149661016 hasRelatedWork W3147848727 @default.
- W3149661016 hasRelatedWork W3152325233 @default.
- W3149661016 isParatext "false" @default.
- W3149661016 isRetracted "false" @default.
- W3149661016 magId "3149661016" @default.
- W3149661016 workType "article" @default.