Matches in SemOpenAlex for { <https://semopenalex.org/work/W3149674763> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3149674763 endingPage "348" @default.
- W3149674763 startingPage "341" @default.
- W3149674763 abstract "We augmented our standard extracorporeal membrane oxygenation laboratory protocol to include antifactor Xa assays, thromboelastography, and antithrombin measurements. We performed a retrospective chart review to determine outcomes for patients placed on extracorporeal membrane oxygenation (ECMO) prior to and after the initiation of our anticoagulation laboratory protocol. A total of 663 consecutive ECMO runs were evaluated from January 1, 2007 to June 30, 2018. Of these patients, 252 were on ECMO prior to initiation of the anticoagulation laboratory protocol on September 1, 2011, and 411 patients were on ECMO after initiation of the protocol. There were no major changes to our extracorporeal membrane oxygenation circuit or changes to our transfusion threshold during this continuous study period. Transfusion utilization data revealed statistically significant decreases in almost all blood components, and a savings in blood component inflation-adjusted acquisition costs of 31% bringing total blood product cost-savings to $309,905 per year. In addition, there was an increase in survival to hospital discharge from 45 to 56% associated with the initiation of the protocol ( p = 0.004). Our data indicate that implementation of a standardized ECMO anticoagulation protocol, which titrates unfractionated heparin infusions based on antifactor Xa assays, is associated with reduced blood product utilization, significant blood product cost savings, and increased patient survival. Future prospective evaluation is needed to establish an antifactor Xa assay-driven ECMO anticoagulation strategy as both clinically superior and cost-effective." @default.
- W3149674763 created "2021-04-13" @default.
- W3149674763 creator A5009050263 @default.
- W3149674763 creator A5013928675 @default.
- W3149674763 creator A5024624509 @default.
- W3149674763 creator A5043249165 @default.
- W3149674763 creator A5051980537 @default.
- W3149674763 creator A5056293140 @default.
- W3149674763 creator A5069557492 @default.
- W3149674763 date "2021-04-01" @default.
- W3149674763 modified "2023-09-26" @default.
- W3149674763 title "The Use of Antifactor Xa Assays in a Comprehensive Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Protocol is Associated with Increased Survival and Significant Blood Product Cost-Savings" @default.
- W3149674763 cites W1966262163 @default.
- W3149674763 cites W1989940253 @default.
- W3149674763 cites W2001278798 @default.
- W3149674763 cites W2017030031 @default.
- W3149674763 cites W2025344496 @default.
- W3149674763 cites W2028314706 @default.
- W3149674763 cites W2034361397 @default.
- W3149674763 cites W2052917878 @default.
- W3149674763 cites W2065395094 @default.
- W3149674763 cites W2082416969 @default.
- W3149674763 cites W2109077832 @default.
- W3149674763 cites W2139260696 @default.
- W3149674763 cites W2171632810 @default.
- W3149674763 cites W2285071347 @default.
- W3149674763 cites W2333872518 @default.
- W3149674763 cites W2505941984 @default.
- W3149674763 cites W2612314963 @default.
- W3149674763 cites W2618577309 @default.
- W3149674763 cites W2734546026 @default.
- W3149674763 cites W2755049322 @default.
- W3149674763 cites W2792875522 @default.
- W3149674763 cites W2950644105 @default.
- W3149674763 cites W3002946619 @default.
- W3149674763 cites W3013450316 @default.
- W3149674763 cites W3016860070 @default.
- W3149674763 doi "https://doi.org/10.1055/s-0041-1726455" @default.
- W3149674763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36388079" @default.
- W3149674763 hasPublicationYear "2021" @default.
- W3149674763 type Work @default.
- W3149674763 sameAs 3149674763 @default.
- W3149674763 citedByCount "0" @default.
- W3149674763 crossrefType "journal-article" @default.
- W3149674763 hasAuthorship W3149674763A5009050263 @default.
- W3149674763 hasAuthorship W3149674763A5013928675 @default.
- W3149674763 hasAuthorship W3149674763A5024624509 @default.
- W3149674763 hasAuthorship W3149674763A5043249165 @default.
- W3149674763 hasAuthorship W3149674763A5051980537 @default.
- W3149674763 hasAuthorship W3149674763A5056293140 @default.
- W3149674763 hasAuthorship W3149674763A5069557492 @default.
- W3149674763 hasConcept C126322002 @default.
- W3149674763 hasConcept C141071460 @default.
- W3149674763 hasConcept C177713679 @default.
- W3149674763 hasConcept C194828623 @default.
- W3149674763 hasConcept C2776858399 @default.
- W3149674763 hasConcept C2777396833 @default.
- W3149674763 hasConcept C2777557582 @default.
- W3149674763 hasConcept C2777664302 @default.
- W3149674763 hasConcept C2778382381 @default.
- W3149674763 hasConcept C2779026020 @default.
- W3149674763 hasConcept C42219234 @default.
- W3149674763 hasConcept C71924100 @default.
- W3149674763 hasConceptScore W3149674763C126322002 @default.
- W3149674763 hasConceptScore W3149674763C141071460 @default.
- W3149674763 hasConceptScore W3149674763C177713679 @default.
- W3149674763 hasConceptScore W3149674763C194828623 @default.
- W3149674763 hasConceptScore W3149674763C2776858399 @default.
- W3149674763 hasConceptScore W3149674763C2777396833 @default.
- W3149674763 hasConceptScore W3149674763C2777557582 @default.
- W3149674763 hasConceptScore W3149674763C2777664302 @default.
- W3149674763 hasConceptScore W3149674763C2778382381 @default.
- W3149674763 hasConceptScore W3149674763C2779026020 @default.
- W3149674763 hasConceptScore W3149674763C42219234 @default.
- W3149674763 hasConceptScore W3149674763C71924100 @default.
- W3149674763 hasIssue "04" @default.
- W3149674763 hasLocation W31496747631 @default.
- W3149674763 hasLocation W31496747632 @default.
- W3149674763 hasOpenAccess W3149674763 @default.
- W3149674763 hasPrimaryLocation W31496747631 @default.
- W3149674763 hasRelatedWork W1921148719 @default.
- W3149674763 hasRelatedWork W1968334582 @default.
- W3149674763 hasRelatedWork W2603934635 @default.
- W3149674763 hasRelatedWork W2902978416 @default.
- W3149674763 hasRelatedWork W2907087666 @default.
- W3149674763 hasRelatedWork W2991186121 @default.
- W3149674763 hasRelatedWork W3038996428 @default.
- W3149674763 hasRelatedWork W3149674763 @default.
- W3149674763 hasRelatedWork W4213282892 @default.
- W3149674763 hasRelatedWork W97950759 @default.
- W3149674763 hasVolume "11" @default.
- W3149674763 isParatext "false" @default.
- W3149674763 isRetracted "false" @default.
- W3149674763 magId "3149674763" @default.
- W3149674763 workType "article" @default.