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- W3149677075 abstract "Autophagy 在服的局部缺血起一个重要作用并且可以是为为击开发新奇治疗的一个潜在的目标。在这研究，我们由分析与 autophagy 和 ischemic 击有关的基因构造了一个 autophagy 相关的小径网络，并且风险基因被屏蔽。二个 autophagy 相关的模块显著地起来调整、聚类影响服的局部缺血。而且，三关键模块化的基因(NFKB1， RELA，和 STAT3 ) 被揭示。与 5 褶层十字确认， NFKB1， RELA，和 STAT3 的 ROC 曲线是 0.8256， 0.8462，和 0.8923。他们形成了一个复杂模块并且竞争地调停了在服的局部缺血的 autophagy 的激活。在结论，包含 NFKB1， RELA，和 STAT3 的一个模块调停 autophagy，为 ischemic 的诊断和治疗用作潜在的 biomarker 中风。" @default.
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- W3149677075 date "2015-01-01" @default.
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- W3149677075 title "Identification of autophagy signaling network that contributes to stroke in the ischemic rodent brain via gene expression" @default.
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