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- W3149792570 abstract "开发神经原和成熟外部神经系统(PNS ) 神经原的 axonal 分隔空间有能力局部地综合蛋白质。综合 Axonally 的蛋白质被显示了在开发中央神经系统(CNS ) 和 PNS 神经原便于 axonal pathfinding 和维护，并且便于成熟 PNS 神经原的新生。有教养的神经原的轴突的介绍 RNA 研究显示出 mRNAs 的一张令人惊讶地复杂的人口为无数功能编码蛋白质。尽管经典出现的不平的 endoplasmic 蜂窝胃(RER ) ，光滑的 endoplasmic 蜂窝胃(嗯) 并且 Golgi 仪器没被 ultrastructural 研究， axonal RNA 介绍研究表演几膜和产品其翻译将需要存取到局部性的能分泌的机制的分泌编码蛋白质的 mRNAs 在轴突记录了。我们以前证明有教养的神经原的轴突包含 RER 和 Golgi 仪器的功能的等价物。这里，我们证明为信号识别粒子的标记， RER，嗯，并且 Golgi 仪器在在 vivo 的 PNS 轴突是在场的。这些蛋白质的合作本地化反射为局部地翻译的蛋白质对 axoplasmic 膜局部性的有教养的轴突看那。而且，神经损害增加这些蛋白质的层次或聚集，建议再生轴突为膜指向局部地综合的蛋白质有一个增加的能力。" @default.
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- W3149792570 date "2013-01-01" @default.
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- W3149792570 title "Peripheral nerve axons contain machinery for co-translational secretion of axonally-generated proteins" @default.
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