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- W3150151399 abstract "作为光力学的 sensitizers 和 anticancer 药包括卟啉的联合 anticancer 形式是为许多研究人员的一个有趣的题目。在这研究， photochemotherapeutic 效果由 tetracationic meso-tetrakis (N-methyl-4-pyridyl ) 的同时的 photoactivation 调停了 porphine tetratosylate (TMPyP ) 和 adriamycin (ADM ) 用人的 hepatocellular 癌房间线(HePG2 ) 被探索。在黑暗中并且面对 photoirradiation 与 ADM 在音乐会行动的 TMPyP 的效率被评估，由独立，作为合作混合学习在在有每二个代理人的孵化以后的房间的房间生存能力， caspase-3 活动和 ultrastructural 变化。在黑暗条件下面，有 TMPyP 和 ADM 的房间的同时的孵化显著地分别地由 1.8 褶层和 1.3 褶层提高了房间死亡，与 TMPyP 或 ADM 处理相比。在 photoirradiation 以后，有 TMPyP 和 ADM 的合作处理的 antiproliferative 效果由 2 褶层进一步增加了。传播电子显微镜学和在对待的房间的 caspase-3 层次的大小表明有轻照耀跟随的 ADM 和 TMPyP 的房间的合作处理向坏死指导了房间死亡并且废除了 apoptotic 房间死亡小径，它在在缺席并且在 photoirradiation 的存在与 ADM 对待的房间被展出。" @default.
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- W3150151399 date "2009-01-01" @default.
- W3150151399 modified "2023-09-23" @default.
- W3150151399 title "Evaluating the antitumor activity of combined photochemotherapy mediated by a meso-substituted tetracationic porphyrin and adriamycin" @default.
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