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- W3150178369 abstract "Hyperactivaion of immme system is considered by most investigators as importantfactor, contributing to progression of HIV-infection and development ofAIDS. In the review modern knowledge about mechanisms and results of activation of immune system during HIV-infection are presented. HIV itself, opportunistic pathogens and components of gut microbiota, first of all, endotoxins ofgram-negative bacteria are considered as probable activators of immune system. High levels of endotoxin and markers of immune activation are associated with an even greater rate of progression of HIV-infection." @default.
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- W3150178369 date "2012-06-15" @default.
- W3150178369 modified "2023-09-26" @default.
- W3150178369 title "ON THE QUESTION OF THE PATHOGENESIS OF HIV-INFECTION: THE ROLE OF IMMUNE ACTIVATION IN PROGRESSION OF DISEASE" @default.
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- W3150178369 doi "https://doi.org/10.17816/eid40663" @default.
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